Journal
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Volume -, Issue -, Pages -Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/cjn.2023.36
Keywords
Acute ischemic stroke; Direct to angio transfer; Endovascular therapy; Large vessel occlusion; Mobile stroke unit; Reperfusion
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This study retrospectively analyzed the experience of using a mobile stroke unit (MSU) for direct to angiosuite (DTAS) transfer in patients with acute ischemic stroke (AIS). The results showed that the DTAS strategy can reduce the workflow time for endovascular thrombectomy (EVT).
Background:Early reperfusion has the best likelihood for a favorable outcome in acute ischemic stroke (AIS) with large vessel occlusion (LVO). Our experience with mobile stroke unit (MSU) for direct to angiosuite (DTAS) transfer in AIS patients with suspected LVO is presented. Methods:Retrospective review of prospectively collected data from November 2019 to August 2022, of patients evaluated and transferred by the University of Alberta Hospital MSU and moved to angiosuite for endovascular thrombectomy (EVT). Result:A total of 41 cases were included. Nine were chosen for DTAS and 32 were shifted to angiosuite after stopping for computed tomography (CT) angiography of the head and neck (no-DTAS). Stroke severity measured by NIHSS (median with interquartile range (IQR)) was higher in patients of DTAS, 22 (14-24) vs 14.5 (5-25) in no-DTAS (p = 0.001). The non-contrast CT head in MSU showed hyperdense vessels in 8 (88.88%) DTAS vs 11 (34.35%) no-DTAS patients (p = 0.003). The EVT timelines (median with IQR, 90(th) percentile) including door to artery puncture time were 31 (23-50, 49.2) vs 79 (39-264, 112.8) minutes, and door to recanalization time was 69 (49-110, 93.2) vs 105.5 (52-178, 159.5) minutes in DTAS vs no-DTAS group, respectively. The workflow times were significantly shorter in the DTAS group (p < 0.001). Eight (88.88%) out of 9 DTAS patients had LVO and underwent thrombectomy. Conclusions:MSU for DTAS in patients with high NIHSS scores, cortical signs, and CT showing hyperdense vessel is an effective strategy to reduce the EVT workflow time.
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