Journal
BRITISH JOURNAL OF PSYCHIATRY
Volume 222, Issue 5, Pages 204-211Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.2023.8
Keywords
ALSPAC; co-occurrence; within-family transmission; psychopathology; treatment targets
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Using network analysis, this study examined the co-occurrence of depression symptoms in parents and its impact on child emotional well-being. The study identified bridge symptoms that reinforce depression symptoms between parents and their association with child emotional difficulties. These findings provide potential therapeutic targets for treating co-occurring depression in parents and reducing vulnerability in children.
BackgroundMother and father depression symptoms often co-occur, and together can have a substantial impact on child emotional well-being. Little is understood about symptom-level mechanisms underlying the co-occurrence of depression symptoms within families. AimsThe objective was to use network analysis to examine depression symptoms in mothers and fathers after having a baby, and emotional symptoms in children in early adolescence. MethodWe examined data from 4492 mother-father-child trios taken from a prospective, population-based cohort in the UK. Symptoms were examined using two unregularised partial correlation network models. The initial model was used to examine the pattern of associations, i.e. the overall network structure, for mother and father depression symptoms, and then to identify bridge symptoms that reinforce depression symptoms between parents during offspring infancy. The second model examined associations between the parent symptom network, including bridge symptoms, with later child emotional difficulties. ResultsThe study included 4492 mother-father-child trios; 2204 (49.1%) children were female. Bridge symptoms reinforcing mother and father depression symptoms were feeling guilty and self-harm ideation. For mothers, the bridge symptom of feeling guilty, and symptoms of anhedonia, panic and sadness were highly connected with child emotional difficulties. For fathers, the symptom of feeling overwhelmed associated with child emotional difficulties. Guilt and anhedonia in fathers appeared to indirectly associate with child emotional difficulties through the same symptom in mothers. ConclusionsOur findings suggest that specific symptom cascades are central for co-occurring depression in parents and increased vulnerability in children, providing potential therapeutic targets.
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