Related references
Note: Only part of the references are listed.Intestinal pathophysiological abnormalities in steady state and after vaso-occlusive crisis in murine sickle cell disease
Maria Poplawska et al.
BRITISH JOURNAL OF HAEMATOLOGY (2022)
Genes modulating intestinal permeability and microbial community are dysregulated in sickle cell disease
Maria Poplawska et al.
ANNALS OF HEMATOLOGY (2022)
Improvement of hemolytic anemia with GBT1118 is renoprotective in transgenic sickle mice
Guohui Ren et al.
Blood Advances (2022)
Very low incidence of Clostridioides difficile infection in pediatric sickle cell disease patients
Philip Lee et al.
HAEMATOLOGICA (2021)
Increased hemoglobin affinity for oxygen with GBT1118 improves hypoxia tolerance in sickle cell mice
Kobina Dufu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2021)
Vaso-occlusive crisis in sickle cell disease: a vicious cycle of secondary events
Tim Jang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2021)
The gut microbiome in sickle cell disease: Characterization and potential implications
Hassan Brim et al.
PLOS ONE (2021)
Hematopoietic Stem Cell Transplant for Sickle Cell Disease: PATIENT SELEction and Timing Based on Sickle Cell-Related Multiple Chronic Conditions
Tim Jang et al.
CELL TRANSPLANTATION (2021)
Impact of Pharmacologically Left Shifting the Oxygen-Hemoglobin Dissociation Curve on Arterial Blood Gases and Pulmonary Gas Exchange During Maximal Exercise in Hypoxia
Glenn M. Stewart et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2021)
Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model
Celeste K. Kanne et al.
FRONTIERS IN PHYSIOLOGY (2021)
The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression
Vikash Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine
Rashi Singhal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Low Incidence of Hospital-Onset Clostridium difficile Infection in Sickle Cell Disease
Jibran Ahmed et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Intestinal injury and gut permeability in sickle cell disease
Dibyendu Dutta et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease
Elliott Vichinsky et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Depletion of Intestinal Microbiome Partially Rescues Bone Loss in Sickle Cell Disease Male Mice
Sara Tavakoli et al.
SCIENTIFIC REPORTS (2019)
Rifaximin for sickle cell disease
Seah H. Lim et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Elevated urinary 3-indoxyl sulfate in sickle cell disease
Dibyendu Dutta et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression
Bruce R. Stevens et al.
GUT (2018)
Intestinal microbiome analysis revealed dysbiosis in sickle cell disease
Seah H. Lim et al.
AMERICAN JOURNAL OF HEMATOLOGY (2018)
GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury
Nathan D. Putz et al.
JOURNAL OF APPLIED PHYSIOLOGY (2018)
A Phase 3 Trial of L-Glutamine in Sickle Cell Disease
Yutaka Niihara et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells
Gera Goverse et al.
JOURNAL OF IMMUNOLOGY (2017)
Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease
K. I. Ataga et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children
Anika Nier et al.
PLOS ONE (2017)
Hypoxia and Mucosal Inflammation
Sean P. Colgan et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)
Tumor necrosis factor and lymphotoxin in regulation of intestinal inflammation
E. O. Gubernatorova et al.
BIOCHEMISTRY-MOSCOW (2016)
GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease
Donna Oksenberg et al.
BRITISH JOURNAL OF HAEMATOLOGY (2016)
Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia
Leon Zheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
Methods to determine intestinal permeability and bacterial translocation during liver disease
Lirui Wang et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2015)
Neutrophil ageing is regulated by the microbiome
Dachuan Zhang et al.
NATURE (2015)
Intestinal permeability - a new target for disease prevention and therapy
Stephan C. Bischoff et al.
BMC GASTROENTEROLOGY (2014)
Mast Cell Activation in Sickle Mice Stimulates Endothelial Dysfunction
Kathryn Luk et al.
BLOOD (2014)
Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition
Masami Wada et al.
GASTROENTEROLOGY (2013)
TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis
Liping Su et al.
GASTROENTEROLOGY (2013)
Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates
Frederic B. Piel et al.
LANCET (2013)
Commensal Akkermansia muciniphila Exacerbates Gut Inflammation in Salmonella Typhimurium-Infected Gnotobiotic Mice
Bhanu Priya Ganesh et al.
PLOS ONE (2013)
Pathobionts of the gastrointestinal microbiota and inflammatory disease
Janet Chow et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases
Benoit Chassaing et al.
GASTROENTEROLOGY (2011)
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Kendle M. Maslowski et al.
NATURE (2009)
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
Christina M. Van Itallie et al.
JOURNAL OF CELL SCIENCE (2008)
Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo
DR Clayburgh et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
FJ Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
MR Amieva et al.
SCIENCE (2003)
Differential modulation of enterocyte-like Caco-2 cells after exposure to short-chain fatty acids
JJ Malago et al.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT (2003)
Claudins create charge-selective channels in the paracellular pathway between epithelial cells
OR Colegio et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)