Twenty-four-hour ambulatory blood pressure monitoring-from silent to whispering brain damage

Article Peripheral Vascular Disease

Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community

Ramachandran S. Vasan et al.

Summary: This study examined the prevalence, correlates, and prognosis of hypertension-mediated organ damage (HMOD) in a community-based study. The findings showed that the prevalence of HMOD varied across different blood pressure guidelines and that the presence of HMOD increased the risk of cardiovascular disease.

HYPERTENSION (2022)

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Article Cardiac & Cardiovascular Systems

Plasticity of cerebral microvascular structure and mechanics during hypertension and following recovery of arterial pressure

Rasna Sabharwal et al.

Summary: Changes in vascular structure, such as arteriolar wall thickness, diameter, wall-to-lumen ratio, and biological stiffness, rapidly change during hypertension and recover with blood pressure. However, inward remodeling develops slowly and does not recover. This lack of recovery of arteriolar diameter has implications for the long-term impact of hypertension on vascular determinants of brain health.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2022)

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Article Peripheral Vascular Disease

Routine assessment of cognitive function in older patients with hypertension seen by primary care physicians: why and how-a decision-making support from the working group on 'hypertension and the brain' of the European Society of Hypertension and from the European Geriatric Medicine Society

Angelo Scuteri et al.

Summary: The European Societies of Hypertension and Cardiology guidelines have recognized cognitive function decline as a hypertension-mediated organ damage, which can be the only hypertension-mediated organ damage in over 30% of hypertensive patients. It is crucial for the medical community to have a pragmatic approach to identify and treat these patients early. Moreover, there is a clear connection between exposure to high blood pressure and the development of cognitive decline, making it necessary to standardize clinical evaluation and treatment practices for hypertensive patients, especially in older populations.

JOURNAL OF HYPERTENSION (2021)

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Editorial Material Clinical Neurology

The Ambibaric Brain Pathophysiological and Clinical Implications

Vladimir Hachinski et al.

Summary: The article introduces a new evolutionary interpretation of the brain's circulation, emphasizing the importance of balancing low-pressure and high-pressure systems for optimal brain health.

STROKE (2021)

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Review Neurosciences

Implications of Circadian Rhythm in Stroke Occurrence: Certainties and Possibilities

Dana Marieta Fodor et al.

Summary: Stroke occurrence follows a circadian rhythmicity pattern, correlating with both exogenous and endogenous factors. Disruption of the internal clock may increase the risk of stroke and affect neuronal susceptibility to injury and rehabilitation.

BRAIN SCIENCES (2021)

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Article Clinical Neurology