Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 159, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2022.114195
Keywords
Multiple sclerosis; Chronic inflammatory disease; Probiotics; Microbiota
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Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system and results in nerve demyelination. The exact cause of MS is unknown, but regulating the immune system and inhibiting inflammatory pathways may have positive effects on disease control and improvement. Studies have shown that probiotics can modulate the gut microbiome, thus impacting the immune system and inflammatory responses in MS patients. The findings indicate that probiotics have a beneficial effect on the recovery of both human and animal MS patients. This review article explores the impact of probiotics on immune cells and inflammatory cytokines, highlighting their potential therapeutic mechanisms and role in disease management and control.
Multiple sclerosis (MS) is known as a chronic inflammatory disease (CID) that affects the central nervous system and leads to nerve demyelination. However, the exact cause of MS is unknown, but immune system regulation and inhibiting the function of inflammatory pathways may have a beneficial effect on controlling and improving the disease. Studies show that probiotics can alter the gut microbiome, thereby improving and affecting the immune system and inflammatory responses in patients with MS. The results show that probiotics have a good effect on the recovery of patients with MS in humans and animals. The present study investigated the effect of probiotics and possible therapeutic mechanisms of probiotics on immune cells and inflammatory cytokines. This review article showed that probiotics could improve immune cells and inflammatory cytokines in patients with MS and can play an effective role in disease management and control.
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