Role of flavonoids in age-related macular degeneration

A common eye disorder known as age-related macular degeneration (AMD) eventually results in blindness and vision loss. AMD has a complicated and poorly understood aetiology. The main pathological processes associated with AMD include oxidative damage, inflammation, and neovascularization. Flavonoids are naturally occurring bioactive substances with extensive distribution and antioxidant, anti-inflammatory, and neovascularization inhibitory properties. Several in vitro and in vivo AMD-related models pertinent to vision and this ocular ailment have been used to assess the mechanisms of action of various flavonoids. This article will discuss the research progress of flavonoids in AMD, especially the characteristics and mechanism of flavonoids in treating AMD.

Automated summary

Age-related macular degeneration (AMD) is a common eye disorder that leads to blindness and vision loss. The underlying causes of AMD are not well understood, but oxidative damage, inflammation, and neovascularization are believed to play a role. Flavonoids, naturally occurring bioactive substances with antioxidant, anti-inflammatory, and neovascularization inhibitory properties, have been studied in relation to AMD using in vitro and in vivo models. This article discusses the research progress and characteristics of flavonoids in treating AMD.