☆ 4.8 Article

Ultrasonic-controlled ?explosive? hydrogels to precisely regulate spatiotemporal osteoimmune disturbance

BIOMATERIALS (2023)

Related references

Note: Only part of the references are listed.

Article Engineering, Biomedical

A biomimetic and bioactive scaffold with intelligently pulsatile teriparatide delivery for local and systemic osteoporosis regeneration

Lingbin Che et al.

Summary: Osteoporosis is a serious consequence of aging, leading to disability and death. This study develops a biomimetic drug delivery system that can release medication in a sensitive and short-term manner, providing an effective treatment for osteoporosis.

BIOACTIVE MATERIALS (2023)

Add to Collection

Article Chemistry, Multidisciplinary

Self-Healing Hydrogel Embodied with Macrophage-Regulation and Responsive-Gene-Silencing Properties for Synergistic Prevention of Peritendinous Adhesion

Chuandong Cai et al.

Summary: Antiadhesion barriers are crucial for preventing the formation of adhesion tissue after tendon surgery. A self-healing and deformable hyaluronic acid (HA) hydrogel was developed with matrix metalloproteinase-2 (MMP-2)-degradable gelatin-methacryloyl (GelMA) microspheres (MSs) encapsulated with Smad3-siRNA nanoparticles to inhibit fibroblast proliferation and prevent peritendinous adhesion. The proposed self-healing hydrogel antiadhesion barrier with MMP-2-responsive drug release behavior effectively decreases inflammation and inhibits tendon adhesion, presenting a new strategy for the development of safe and effective antiadhesion barriers.

ADVANCED MATERIALS (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Ultrasound-Responsive Systems as Components for Smart Materials

Athanasios G. Athanassiadis et al.

Summary: Smart materials can utilize ultrasound to control and initiate physical and chemical systems with high specificity. The emerging techniques in this field offer great potential for the development of smart capabilities supported by ultrasound, while also raising interesting questions for further research.

CHEMICAL REVIEWS (2022)

Add to Collection

Article Multidisciplinary Sciences

Engineering immunomodulatory and osteoinductive implant surfaces via mussel adhesion-mediated ion coordination and molecular clicking

Tao Wang et al.

Summary: In this study, a dual-effect coating was designed to modulate the osteoimmune microenvironment and enhance bone regeneration. The coating, which immobilized immunomodulatory metal ions and osteoinductive growth factors, significantly increased the recruitment of M2 macrophages and upregulated the expression of M2 cytokines. This led to improved bone-implant mechanical fixation and new bone ingrowth.

NATURE COMMUNICATIONS (2022)

Add to Collection

Article Engineering, Environmental

Osteoimmunomodulatory injectable Lithium-Heparin hydrogel with Microspheres/TGF-β1 delivery promotes M2 macrophage polarization and osteogenesis for guided bone regeneration

Donghai Li et al.

Summary: This study presents a bone regeneration strategy using an osteoimmunomodulatory biomaterial platform that promotes M2 macrophage polarization and osteogenesis, which has potential for bone repair and regeneration.

CHEMICAL ENGINEERING JOURNAL (2022)

Add to Collection

Article Engineering, Biomedical

Exhausted local lactate accumulation via injectable nanozyme-functionalized hydrogel microsphere for inflammation relief and tissue regeneration

Jieliang Shen et al.

Summary: A injectable microsphere (MS@MCL) for local lactate exhaustion was developed by grafting a composite nanozyme on microspheres, achieving a long-term lactate exhaustion effect. The microspheres synthesized by microfluidic technology is beneficial for injection therapy and improving encapsulation efficiency. The MS@MCL showed potential in eliminating oxidative stress, promoting extracellular matrix metabolism and cell survival.

BIOACTIVE MATERIALS (2022)

Add to Collection

Article Nanoscience & Nanotechnology

Intracellular miRNA Imaging Based on a Self-Powered and Self-Feedback Entropy-Driven Catalyst-DNAzyme Circuit

Chao Xing et al.

Summary: The study demonstrates a self-powered and self-feedback DNAzyme amplification circuit using MnO2 nanosheet-mediated entropy-driven catalyst (EDC)-DNAzyme nanoprobe for sensitive imaging of intracellular microRNA. This strategy provides a versatile approach for the construction of self-powered and self-feedback DNA circuits, enabling effective detection of intracellular molecules with enhanced sensitivity.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection

Review Cell & Tissue Engineering

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

Hongpu Wei et al.

Summary: Bone defects combined with tumors, infections, or other bone diseases are challenging in clinical practice. To address this problem, researchers have designed various implantable biomaterials that can play a role in bone therapy and regeneration. External physical stimuli, endogenous disease microenvironments, and multiple integrated strategies can improve bone tissue therapy and regeneration.

BONE RESEARCH (2022)

Add to Collection

Article Engineering, Biomedical

Resolution of inflammation in bone regeneration: From understandings to therapeutic applications

Hunter Newman et al.

Summary: Impaired bone healing affects 5-10% of cases after injury, with timely resolution of inflammation being crucial for normal healing. Modulating the initial inflammatory phase and promoting its resolution can create a pro-regenerative environment for bone regeneration.

BIOMATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Release of basic fibroblast growth factor from acoustically-responsive scaffolds promotes therapeutic angiogenesis in the hind limb ischemia model

Hai Jin et al.

Summary: A hydrogel-based delivery system for growth factors with modulated release by focused ultrasound was successfully utilized to prevent critical limb ischemia in a preclinical model. In vivo, the combination of acoustically-responsive scaffolds (ARS) and FUS showed superior efficacy compared to other groups, with more perfusion and less necrosis, significantly increased angiogenesis, and reduced fibrosis.

JOURNAL OF CONTROLLED RELEASE (2021)

Add to Collection

Review Engineering, Biomedical

The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time

Claudia Schlundt et al.

Summary: Macrophages are a highly plastic and multifunctional cell population found in all tissues of the human body. In bone, different subpopulations of macrophages play essential roles in the cascade of regeneration and reconstitution, participating in both the inflammatory phase and later phases of healing. The M1/M2 paradigm may not fully capture the dynamic plasticity of macrophages, and understanding the specific mechanisms driving macrophage function in impaired healing scenarios could lead to new therapeutic targets.

ACTA BIOMATERIALIA (2021)

Add to Collection

Review Engineering, Biomedical

Promoting musculoskeletal system soft tissue regeneration by biomaterial-mediated modulation of macrophage polarization

Jinchun Ye et al.

Summary: Studies have shown that active modulation of immune cells, particularly macrophages, via biomaterials is an effective way to control immune response, promote tissue regeneration, and facilitate biomaterial integration.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Synergistic anti-inflammatory and osteogenic n-HA/resveratrol/chitosan composite microspheres for osteoporotic bone regeneration

Limei Li et al.

Summary: This study developed nano-hydroxyapatite/resveratrol/chitosan composite microspheres for promoting bone formation and inflammation reduction. The controlled release of resveratrol improved cell adhesion, proliferation, and osteogenic differentiation, leading to enhanced bone regeneration and fracture healing in osteoporotic conditions, indicating promising multifunctional fillers for osteoporotic bone defect/fracture treatment.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair

Xiaoyu Han et al.

Summary: A composite scaffold inspired by lotus seedpods was developed, utilizing deferoxamine (DFO) release to promote rapid growth of internal blood vessels and enhance vascular formation and osteogenic differentiation, ultimately reducing bone repair time significantly.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Multidisciplinary Sciences

Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing

Chen Hu et al.

Summary: The study demonstrated that the structural properties of biomaterials can influence cell behavior and immune responses, with electrospun membranes of different surface topographies affecting wound healing and immunomodulatory properties. Single-cell RNA sequencing revealed diverse immune cell heterogeneity in vivo, and the aligned scaffold accelerated the immune response towards an adaptive immunity-dominant stage. The microenvironment around scaffolds exhibited intricate interactions between immune and cutaneous cells.

SCIENCE ADVANCES (2021)

Add to Collection

Article Engineering, Biomedical

Wnt signaling modulates macrophage polarization and is regulated by biomaterial surface properties

Jefferson O. Abaricia et al.

BIOMATERIALS (2020)

Add to Collection

Review Pharmacology & Pharmacy

Ultrasound-Responsive Materials for Drug/Gene Delivery

Xiaowen Cai et al.

FRONTIERS IN PHARMACOLOGY (2020)

Add to Collection

Article Multidisciplinary Sciences

Hydration-Enhanced Lubricating Electrospun Nanofibrous Membranes Prevent Tissue Adhesion

Liang Cheng et al.

RESEARCH (2020)

Add to Collection

Review Pharmacology & Pharmacy

Spatiotemporal delivery of bioactive molecules for wound healing using stimuli-responsive biomaterials

Nuria Oliva et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Add to Collection

Review Immunology

Time Course of Immune Response and Immunomodulation During Normal and Delayed Healing of Musculoskeletal Wounds

Preeti J. Muire et al.

FRONTIERS IN IMMUNOLOGY (2020)

Add to Collection

Review Endocrinology & Metabolism

Modulation of the Inflammatory Response and Bone Healing

Masahiro Maruyama et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection

Article Chemistry, Physical

Effect of GelMA Hydrogel Coatings on Corrosion Resistance and Biocompatibility of MAO-Coated Mg Alloys

Wenxian Weng et al.

MATERIALS (2020)

Add to Collection

Article Engineering, Biomedical

Rapid printing of bio-inspired 3D tissue constructs for skin regeneration

Feifei Zhou et al.

BIOMATERIALS (2020)

Add to Collection

Article Engineering, Biomedical

Near-infrared light control of bone regeneration with biodegradable photothermal osteoimplant

Liping Tong et al.

BIOMATERIALS (2019)

Add to Collection

Review Immunology

Targeting Interleukin-6 Signaling in Clinic

Sujin Kang et al.

IMMUNITY (2019)

Add to Collection

Article Food Science & Technology

A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways

Yue Hou et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2019)

Add to Collection

Review Cell Biology

Mechanisms of 3D cell migration

Kenneth M. Yamada et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Add to Collection

Article Cell & Tissue Engineering

Precise immunomodulation of the M1 to M2 macrophage transition enhances mesenchymal stem cell osteogenesis and differs by sex

K. Nathan et al.

BONE & JOINT RESEARCH (2019)

Add to Collection

Article Materials Science, Biomaterials

Biphasic Injectable Bone Cement with Fe3O4/GO Nanocomposites for the Minimally Invasive Treatment of Tumor-Induced Bone Destruction

Feifei Yan et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy

Yixin Zhong et al.

ACS NANO (2019)

Add to Collection

Review Pharmacology & Pharmacy

Delivery of cellular factors to regulate bone healing

Alexander Haumer et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Add to Collection

Article Biotechnology & Applied Microbiology

Resveratrol delivery by ultrasound-mediated nanobubbles targeting nucleus pulposus cells

Jieliang Shen et al.

NANOMEDICINE (2018)

Add to Collection

Article Pharmacology & Pharmacy

Resveratrol stimulation induces interleukin-8 gene transcription via NF-κB

Gerald Thiel et al.

PHARMACOLOGICAL RESEARCH (2018)

Add to Collection

Article Medicine, Research & Experimental

Drug Release from Phase-Changeable Nanodroplets Triggered by Low-Intensity Focused Ultrasound

Yang Cao et al.

THERANOSTICS (2018)

Add to Collection

Article Medicine, Research & Experimental

Resveratrol counteracts bone loss via mitofilin-mediated osteogenic improvement of mesenchymal stem cells in senescence-accelerated mice

Ya-Jie Lv et al.

THERANOSTICS (2018)

Add to Collection

Article Cell & Tissue Engineering

Resveratrol Promotes Osteogenic Differentiation of Canine Bone Marrow Mesenchymal Stem Cells Through Wnt/Beta-Catenin Signaling Pathway

Xiao-e Zhao et al.

CELLULAR REPROGRAMMING (2018)

Add to Collection

Article Medicine, Research & Experimental

Development of an Accurate and Proactive Immunomodulatory Strategy to Improve Bone Substitute Material-Mediated Osteogenesis and Angiogenesis

Zhi-wei Zheng et al.

THERANOSTICS (2018)

Add to Collection

Review Materials Science, Biomaterials

Strategies for delivering bone morphogenetic protein for bone healing

Howa Begam et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Differences in Healing Patterns of the Bone-Implant Interface between Immediately and Delayed-Placed Titanium Implants in Mouse Maxillae

Taisuke Watanabe et al.

CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH (2016)

Add to Collection

Article Engineering, Biomedical

Resveratrol prevents alveolar bone loss in an experimental rat model of periodontitis

Govinda Bhattarai et al.

ACTA BIOMATERIALIA (2016)

Add to Collection

Article Engineering, Biomedical

Sequential release of nanoparticle payloads from ultrasonically burstable capsules

Stephen Kennedy et al.

BIOMATERIALS (2016)

Add to Collection

Article Medicine, Research & Experimental

Resveratrol ameliorates LPS-induced acute lung injury via NLRP3 inflammasome modulation

Lei Jiang et al.

BIOMEDICINE & PHARMACOTHERAPY (2016)

Add to Collection

Review Biotechnology & Applied Microbiology

Resolution of inflammation: a new therapeutic frontier

James N. Fullerton et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Add to Collection

Review Immunology

Mucosal immunity to pathogenic intestinal bacteria

Araceli Perez-Lopez et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Add to Collection

Review Rheumatology

Fracture healing: mechanisms and interventions

Thomas A. Einhorn et al.

NATURE REVIEWS RHEUMATOLOGY (2015)

Add to Collection

Review Biochemistry & Molecular Biology

Mechanosignaling in Bone Health, Trauma and Inflammation

Derrick M. Knapik et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Add to Collection

Article Engineering, Biomedical

Methotrexate-loaded PLGA nanobubbles for ultrasound imaging and Synergistic Targeted therapy of residual tumor during HIFU ablation

Xuemei Zhang et al.

BIOMATERIALS (2014)

Add to Collection

Article Materials Science, Multidisciplinary

Preparation of alginate-CaCl2 microspheres as resveratrol carriers

Ah Ra Cho et al.

JOURNAL OF MATERIALS SCIENCE (2014)

Add to Collection

Article Medicine, Research & Experimental

Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis

Ali Mobasheri et al.

RESVERATROL AND HEALTH (2013)

Add to Collection

Article Chemistry, Physical

Binding Sites of Resveratrol, Genistein, and Curcumin with Milk α- and β-Caseins

P. Bourassa et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2013)

Add to Collection

Review Immunology

Neutrophil recruitment and function in health and inflammation

Elzbieta Kolaczkowska et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Add to Collection

Review Engineering, Biomedical

Tendon Healing: Repair and Regeneration

Pramod B. Voleti et al.

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 14 (2012)

Add to Collection

Review Rheumatology

Fracture healing under healthy and inflammatory conditions

Lutz Claes et al.

NATURE REVIEWS RHEUMATOLOGY (2012)

Add to Collection

Review Medicine, General & Internal

Bone regeneration: current concepts and future directions

Rozalia Dimitriou et al.

BMC MEDICINE (2011)

Add to Collection

Article Endocrinology & Metabolism

Resveratrol Promotes Osteogenesis of Human Mesenchymal Stem Cells by Upregulating RUNX2 Gene Expression via the SIRT1/FOXO3A Axis

Pei-Chi Tseng et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2011)

Add to Collection

Article Engineering, Biomedical

A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery

Hila Epstein-Barash et al.

BIOMATERIALS (2010)

Add to Collection

Review Multidisciplinary Sciences

Origin and physiological roles of inflammation

Ruslan Medzhitov

NATURE (2008)

Add to Collection

Article Integrative & Complementary Medicine

Effect of resveratrol on NF-kappa B activity in rat peritoneal macrophages

Zhen-Hua Ma et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2006)

Add to Collection

Review Critical Care Medicine

Current concepts of molecular aspects of bone healing

R Dimitriou et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2005)

Add to Collection

Article Chemistry, Applied

Praziquantel-loaded PLGA nanoparticles: preparation and characterization

RM Mainardes et al.

JOURNAL OF MICROENCAPSULATION (2005)

Add to Collection

Article Engineering, Biomedical

The properties of chitosan-gelatin membranes and scaffolds modified with hyaluronic acid by different methods

JS Mao et al.

BIOMATERIALS (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.