Related references
Note: Only part of the references are listed.Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus
Daniel A. Domingo-Lopez et al.
ADVANCED DRUG DELIVERY REVIEWS (2022)
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications
Junjun Ni et al.
BRAIN PATHOLOGY (2022)
Atherosclerosis: Recent developments
Johan L. M. Bjoerkegren et al.
CELL (2022)
Spatially resolved transcriptomics provide a new method for cancer research
Bowen Zheng et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)
Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension
Aditya Surapaneni et al.
KIDNEY INTERNATIONAL (2022)
A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders
Emmanuel O. Adewuyi et al.
COMMUNICATIONS BIOLOGY (2022)
Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
Manli Wang et al.
CANCER CELL (2022)
Favorable Prognostic Impact of Cathepsin H (CTSH) High Expression in Thyroid Carcinoma
Pai Peng et al.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2021)
Characterization of Conventional Dendritic Cells and Macrophages in the Spleen Using the CSF1R-Reporter Transgenic Chickens
Kate M. Sutton et al.
FRONTIERS IN IMMUNOLOGY (2021)
Cathepsin C Regulates Cytokine-Induced Apoptosis in β-Cell Model Systems
Tina Floyel et al.
GENES (2021)
Genetic and environmental factors regulate the type 1 diabetes gene CTSH via differential DNA methylation
Jody Ye et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Single Molecule Assay for Ultrasensitive Detection of Cathepsin B in Human Blood
Bharani Thangavelu et al.
ACS OMEGA (2021)
Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling
Junjun Ni et al.
JOURNAL OF NEUROINFLAMMATION (2021)
Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic beta-Cells
Jamie R. J. Inshaw et al.
DIABETES CARE (2020)
Longitudinal Pattern of First-Phase Insulin Response Is Associated With Genetic Variants Outside the Class II HLA Region in Children With Multiple Autoantibodies
Maarit K. Koskinen et al.
DIABETES (2020)
The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management
Tulasi Yadati et al.
CELLS (2020)
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis
Julien Carvelli et al.
NATURE (2020)
The Rac2 GTPase contributes to cathepsin H-mediated protection against cytokine-induced apoptosis in insulin-secreting cells
Tina Floyel et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
Cysteine cathepsins in extracellular matrix remodeling: Extracellular matrix degradation and beyond
Matej Vizovisek et al.
MATRIX BIOLOGY (2019)
Cysteine Cathepsins and Their Extracellular Roles: Shaping the Microenvironment
Eva Vidak et al.
CELLS (2019)
Combined analysis of keratinocyte cancers identifies novel genome-wide loci
Upekha E. Liyanage et al.
HUMAN MOLECULAR GENETICS (2019)
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain
Junjun Ni et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells
Izumi Ohigashi et al.
CELL REPORTS (2019)
Effects of Five Substances with Different Modes of Action on Cathepsin H, C and L Activities in Zebrafish Embryos
Eberhard Kuester et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2019)
Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE though impairment of toll-like receptor 3 cascade
Ryo Okada et al.
INFLAMMATION RESEARCH (2018)
Crystal structures of human procathepsin H
Yue Hao et al.
PLOS ONE (2018)
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations
Ana Marquez et al.
GENOME MEDICINE (2018)
Inherited diseases caused by mutations in cathepsin protease genes
Stephanie Ketterer et al.
FEBS JOURNAL (2017)
A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
Aishath S. Naeem et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)
The Future of Cysteine Cathepsins in Disease Management
Lovro Kramer et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice
Zhou Wu et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
Follicular thyroglobulin induces cathepsin H expression and activity in thyrocytes
Kenzaburo Oda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity
Nicholas A. Bright et al.
CURRENT BIOLOGY (2016)
Neuroinflammation: the devil is in the details
Damon J. DiSabato et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Genes Affecting β-Cell Function in Type 1 Diabetes
Tina Floyel et al.
CURRENT DIABETES REPORTS (2015)
Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)
Steffen U. Thorsen et al.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2015)
The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation
Kai Fan et al.
JOURNAL OF NEUROINFLAMMATION (2015)
The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage
Junjun Ni et al.
JOURNAL OF NEUROSCIENCE (2015)
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
Suna Onengut-Gumuscu et al.
NATURE GENETICS (2015)
Detection of Mutations in LRPAP1, CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2 in 298 Families With Early-Onset High Myopia by Exome Sequencing
Dan Jiang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
Oakley C. Olson et al.
NATURE REVIEWS CANCER (2015)
SAR studies of differently functionalized chalcones based hydrazones and their cyclized derivatives as inhibitors of mammalian cathepsin B and cathepsin H
Neera Raghav et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
N-formylpyrazolines and N-benzoylpyrazolines as novel inhibitors of mammalian cathepsin B and cathepsin H
N. Raghav et al.
BIOORGANIC CHEMISTRY (2014)
Acyl hydrazides and triazoles as novel inhibitors of mammalian cathepsin B and cathepsin H
Neera Raghav et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Novel compound heterozygous mutations in CTSC gene cause Papillon-Lefevre syndrome with high serum immunoglobulin E
Zhiming Li et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2014)
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
Monica R. P. Elmore et al.
NEURON (2014)
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients
Tina Floyel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
CTSC and Papillon-Lefevre syndrome: detection of recurrent mutations in Hungarian patients, a review of published variants and database update
Nikoletta Nagy et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2014)
Mutations in LRPAP1 Are Associated with Severe Myopia in Humans
Mohammed A. Aldahmesh et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Development of cell-active non-peptidyl inhibitors of cysteine cathepsins
Dibyendu Dana et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Molecular characterisation and expression analysis of the cathepsin H gene from rock bream (Oplegnathus fasciatus)
Ju-Won Kim et al.
FISH & SHELLFISH IMMUNOLOGY (2013)
Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis
Katherine R. Smith et al.
HUMAN MOLECULAR GENETICS (2013)
Galactosialidosis: review and analysis of CTSA gene mutations
Anna Caciotti et al.
ORPHANET JOURNAL OF RARE DISEASES (2013)
ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy
Juliette Faraco et al.
PLOS GENETICS (2013)
Lithium Chloride Enhances Cathepsin H Expression and BMP-4 Degradation in C3H10T1/2 Cells
Koshi N. Kishimoto et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
Regine Bergholdt et al.
DIABETES (2012)
Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation
Audrey D. Lafrenaye et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters
Weiya Douglas Lu et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling
Alejandra Garcia-Cattaneo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
Decio L. Eizirik et al.
PLOS GENETICS (2012)
Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells
S-M Wu et al.
ONCOGENE (2011)
Gene Targeting of the Cysteine Peptidase Cathepsin H Impairs Lung Surfactant in Mice
Frank Buehling et al.
PLOS ONE (2011)
Pulmonary Alveolar Proteinosis
Ajmal Khan et al.
RESPIRATORY CARE (2011)
A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci
Jonathan P. Bradfield et al.
PLOS GENETICS (2011)
Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer
Vasilena Gocheva et al.
BIOLOGICAL CHEMISTRY (2010)
Complement and its role in innate and adaptive immune responses
Jason R. Dunkelberger et al.
CELL RESEARCH (2010)
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation
Benjamin T. Goult et al.
EMBO JOURNAL (2010)
Cathepsin H Is an Additional Convertase of Pro-granzyme B
Michael E. D'Angelo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
Chrystelle Bonnart et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Nicholas J. Anthis et al.
EMBO JOURNAL (2009)
Most mammalian mRNAs are conserved targets of microRNAs
Robin C. Friedman et al.
GENOME RESEARCH (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones
Vivian Hook et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Sortilin mediates the lysosomal targeting of cathepsins D and H
Maryssa Canuel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Cathepsin H and napsin A are active in the alveoli and increased in alveolar proteinosis
M. Woischnik et al.
EUROPEAN RESPIRATORY JOURNAL (2008)
West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction
Jason R. Wilson et al.
JOURNAL OF VIROLOGY (2008)
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
Jason D. Cooper et al.
NATURE GENETICS (2008)
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
Scott L. Friedman
PHYSIOLOGICAL REVIEWS (2008)
A double-headed cathepsin B inhibitor devoid of warhead
Patricia Schenker et al.
PROTEIN SCIENCE (2008)
Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer
J. Decock et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS (2008)
Viral recognition by Toll-like receptors
Gregory M. Barton
SEMINARS IN IMMUNOLOGY (2007)
Structural basis of integrin activation by talin
Kate L. Wegener et al.
CELL (2007)
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
Olga Vasiljeva et al.
CURRENT PHARMACEUTICAL DESIGN (2007)
Complex trait genetics of refractive error
Terri L. Young et al.
ARCHIVES OF OPHTHALMOLOGY (2007)
Cysteine Cathepsins and the cutting edge of cancer invasion
Vasilena Gocheva et al.
CELL CYCLE (2007)
Mouse stefins A1 and A2 (Stfa1 and Stfa2) differentiate between papain-like endo- and exopeptidases
Marko Mihelic et al.
FEBS LETTERS (2006)
Cathepsin D deficiency is associated with a human neurodegenerative disorder
Robert Steinfeld et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Targeting proteases: successes, failures and future prospects
Boris Turk
NATURE REVIEWS DRUG DISCOVERY (2006)
Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
Eija Siintola et al.
BRAIN (2006)
Activation processing of cathepsin H impairs recognition by its propeptide
M Horn et al.
BIOLOGICAL CHEMISTRY (2005)
The cornified envelope: A model of cell death in the skin
E Candi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Plasma cathepsin D isoforms and their active metabolites increase after myocardial infarction and contribute to plasma renin activity
RH Naseem et al.
BASIC RESEARCH IN CARDIOLOGY (2005)
Myopia and associated pathological complications
SM Saw et al.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS (2005)
Processing of pulmonary surfactant protein B by napsin and cathepsin H
T Ueno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen
YP Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
T Cirman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Serum cathepsin H as a potential prognostic marker in patients with colorectal cancer
A Schweiger et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS (2004)
Recombinant human cathepsin H lacking the mini chain is an endopeptidase
O Vasiljeva et al.
BIOCHEMISTRY (2003)
Loss of proteolytically processed filaggrin caused by epidermal deletion of matriptase/MT-SP1
K List et al.
JOURNAL OF CELL BIOLOGY (2003)
Human cathepsin H: Deletion of the mini-chain switches substrate specificity from aminopeptidase to endopeptidase
J Dodt et al.
BIOLOGICAL CHEMISTRY (2003)
Expression of cathepsin H in differentiating rat spermatids: immunoelectron microscopic study
CM Haraguchi et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2003)
Enzymatically modified LDL induces cathepsin H in human monocytes - Potential relevance in early atherogenesis
SR Han et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases
S Jenko et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro
A Premzl et al.
EXPERIMENTAL CELL RESEARCH (2003)
Structural determinants of integrin recognition by Talin
B Garcia-Alvarez et al.
MOLECULAR CELL (2003)
Cysteine protease activity is required for surfactant protein B processing and lamellar body genesis
S Guttentag et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes
F Brasch et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Analysis of a truncated form of cathepsin H in human prostate tumor cells
A Waghray et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Simultaneous analysis of 1176 gene products in normal human aorta and abdominal aortic aneurysms using a membrane-based complementary DNA expression array
WS Tung et al.
JOURNAL OF VASCULAR SURGERY (2001)
Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease
RA Steiner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Post-translational processing of surfactant protein-C proprotein -: Targeting motifs in the NH2-terminal flanking domain are cleaved in late compartments
AL Johnson et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)
Cysteine proteinase cathepsin H in tumours and sera of lung cancer patients: relation to prognosis and cigarette smoking
A Schweiger et al.
BRITISH JOURNAL OF CANCER (2000)
Share Paper
