Evaluation of functional warm ischemia time during controlled donation after circulatory determination of death using normothermic regional perfusion (ECMO-TT): A prospective multicenter cohort study

Review Engineering, Biomedical

Normothermic regional perfusion in liver transplantation from donation after cardiocirculatory death: Technical, biochemical, and regulatory aspects and review of literature

Fabio Melandro et al.

Summary: This systematic review highlights the clinical evidence supporting the use of normothermic regional perfusion in DCD liver transplantation, emphasizing its potential benefits and addressing technical, logistic, and regulatory aspects.

ARTIFICIAL ORGANS (2022)

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Article Gastroenterology & Hepatology

In situ normothermic regional perfusion versus ex situ normothermic machine perfusion in liver transplantation from donation after circulatory death

Kayvan Mohkam et al.

Summary: In situ normothermic regional perfusion (NRP) and ex situ normothermic machine perfusion (NMP) have similar outcomes in liver transplantation and appear to match the expected benchmarks for donation after brain death livers. This study may provide insights for further trial design.

LIVER TRANSPLANTATION (2022)

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Editorial Material Critical Care Medicine

Does Normothermic Regional Perfusion Violate the Ethical Principles Underlying Organ Procurement? No

Les James et al.

CHEST (2022)

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Editorial Material Critical Care Medicine

Does Normothermic Regional Perfusion Violate the Ethical Principles Underlying Organ Procurement? Yes

Matthew DeCamp et al.

CHEST (2022)

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Editorial Material Critical Care Medicine

Normothermic Regional Perfusion Requires Careful Ethical Analysis Before Adoption Into Donation After Circulatory Determination of Death

Harry Peled et al.

CRITICAL CARE MEDICINE (2022)

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Article Immunology

External Validation of the DCD-N Score and a Linear Prediction Model to Identify Potential Candidates for Organ Donation After Circulatory Death: A Nationwide Multicenter Cohort Study

Maaike F. Nijhoff et al.

Summary: This study validated two existing prediction models for identifying potential DCD candidates, showing good discrimination but poor calibration in predicting the probability of death within 60 minutes after WLST. Further construction of a new prediction model on a large dataset is necessary to achieve better calibration.

TRANSPLANTATION (2021)

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Article Critical Care Medicine

Expanding controlled donation after the circulatory determination of death: statement from an international collaborative

Beatriz Dominguez-Gil et al.

Summary: This international collaborative statement aims to promote controlled donation after the circulatory determination of death (cDCDD) programs globally. It emphasizes the importance of determining the prognosis justifying WLST and establishing the standard for determining death based on circulatory criteria.

INTENSIVE CARE MEDICINE (2021)

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Article Social Sciences, Mathematical Methods

Relative distribution analysis in Stata

Ben Jann

Summary: This article discusses the method of relative distribution analysis and introduces Stata software that implements various elements of the methodology. The software, reldist, can estimate relative cumulative distribution, density, polarization, divergence, and other summary measures of relative ranks. It also provides functionalities such as location and shape decompositions and covariate balancing, with statistical inference implemented using influence functions and support for estimation on complex samples.

STATA JOURNAL (2021)

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Article Surgery

Improved short-term outcomes of kidney transplants in controlled donation after the circulatory determination of death with the use of normothermic regional perfusion

Maria Padilla et al.

Summary: NRP in controlled DCDD kidney transplants shows better short-term outcomes compared to RR, with a lower risk of delayed graft function and 1-year graft loss in the NRP group.

AMERICAN JOURNAL OF TRANSPLANTATION (2021)

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Article Surgery