Electron Spin Resonance Study of Free Radicals Induced in Single Crystal of Oxcarbazepine

In the present work, the ESR definition of gamma irradiated oxcarbazepine (OCB) single crystals and the ESR properties of the radicals formed after irradiation were studied at room temperature. Structural defects caused by irradiation in single crystals of OCB have been attributed to the R-1 (C1 = CC = C(C = C1)C2(C(= O)NC(= O)N2)C3 = CC = CC = C3) radical as a result of experimental and simulation methods. The determination of the g value and hyperfine splitting constants of the R-1 radical was deduced from the most accurate simulations. ESR resonance signals persisted in the recorded experimental spectra for a duration of 45 days.

Automated summary

In this study, the ESR definition of gamma irradiated oxcarbazepine single crystals and the ESR properties of the radicals formed after irradiation were investigated at room temperature. The presence of structural defects caused by irradiation in the single crystals of oxcarbazepine was attributed to the R-1 radical through experimental and simulation methods. The g value and hyperfine splitting constants of the R-1 radical were determined through accurate simulations, and the ESR resonance signals were observed for a duration of 45 days in the experimental spectra.