Journal
ADVANCED MATERIALS
Volume 28, Issue 6, Pages 1302-1311Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201502479
Keywords
molecular assembly; nanostructure; drug carriers; selective recognition
Categories
Funding
- National Nature Science Foundation of China [21320102004, 21433010, 21321063]
- National Basic Research Program of China (973 program) [2013CB932800]
Ask authors/readers for more resources
Nanostructured drug-carrier systems promise numerous benefits for drug delivery. They can be engineered to precisely control drug-release rates or to target specific sites within the body with a specific amount of therapeutic agent. However, to achieve the best therapeutic effects, the systems should be designed for carrying the optimum amount of a drug to the desired target where it should be released at the optimum rate for a specified time. Despite numerous attempts, fulfilling all of these requirements in a synergistic way remains a huge challenge. The trend in drug delivery is consequently directed toward integrated multifunctional carrier systems, providing selective recognition in combination with sustained or triggered release. Capsules as vesicular systems enable drugs to be confined for controlled release. Furthermore, carriers modified with recognition groups can enhance the capability of encapsulated drug efficacy. Here, recent advances are reviewed regarding designing and preparing assembled capsules with targeting ligands or size controllable for selective recognition in drug delivery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available