Toward understanding links between the microbiome and neurotransmitters

The gut microbiota modulates neurobiological activity in various animal lineages. This is often proposed to occur through interactions with neurotransmitters and other neuromodulatory molecules in the host. Our commentary will discuss recent research that establishes microbiota-neurotransmitter connections, gaps in current understanding, and outstanding questions that may guide future advances in the field of microbiota-nervous system interactions.

Automated summary

The gut microbiota regulates neurobiological activity in various animal lineages by interacting with neurotransmitters and other neuromodulatory molecules in the host. Recent research has established evidence for microbiota-neurotransmitter connections, but there are still outstanding questions and gaps in our current understanding that may guide future advances in the field of microbiota-nervous system interactions.