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Summary: The benefits of early thromboprophylaxis in symptomatic COVID-19 outpatients remain unclear. This study presents the 90-day results from the OVID phase III trial, which showed that early thromboprophylaxis with enoxaparin did not improve the course of COVID-19 in terms of hospitalization, death, or resolution of symptoms.
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Summary: Infection with the SARS-CoV-2 virus, resulting in COVID-19 disease, is associated with a higher risk of thrombosis, especially venous thrombosis. Thrombosis, including pulmonary thrombi and other venous thromboses, is more common in COVID-19 patients compared to other hospitalized patients. Arterial thrombosis is less common but still documented. Risk factors for thrombosis in COVID-19 patients include duration of symptoms before admission and specific laboratory parameters. Thromboprophylaxis is recommended for all COVID-19 patients upon admission, but the dose and duration of treatment are still debated.
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Maddalena Peghin et al.
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Claudia Ravaglia et al.
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Andreas Zollner et al.
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Infectious Diseases
Michela Antonelli et al.
Summary: Despite the high efficacy of COVID-19 vaccines, some individuals still become infected with SARS-CoV-2 post-vaccination. Risk factors for post-vaccination infection include frailty in older adults, living in deprived areas, and obesity. Vaccination is associated with reduced odds of severe symptoms and long-duration illness. The findings suggest the importance of targeting at-risk populations and maintaining infection control measures even in vaccinated individuals.
LANCET INFECTIOUS DISEASES
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Beate Vestad et al.
Summary: Respiratory dysfunction after COVID-19 is associated with altered gut microbiota and persistently elevated LBP levels. Our results suggest a potential gut-lung axis that should be further investigated in relation to long-term pulmonary dysfunction and long COVID.
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Ziyad Al-Aly et al.
Summary: This study analyzed the US Department of Veterans Affairs national healthcare databases to investigate the occurrence of Long COVID and death risk after breakthrough SARS-CoV-2 infection. The findings showed that vaccination significantly reduced the risk of death and post-acute sequelae but did not eliminate them completely. These results underscore the importance of further research on prevention and post-acute care for breakthrough infections.
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Microbiology
Mart M. Lamers et al.
Summary: This Review explores the recent clinical and experimental advancements in understanding the pathogenesis of SARS-CoV-2, its interactions with host cells, and the role of the immune system in the development of severe disease, with a focus on the mechanisms underlying COVID-19-associated ARDS. The findings suggest that SARS-CoV-2 can infect the lower respiratory tract, causing alveolar damage and dysfunctional immune responses, leading to inflammation and immunopathology. These insights may contribute to the development of new therapeutic interventions against COVID-19.
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PSYCHOLOGICAL MEDICINE
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Laura Fabbri et al.
Summary: This study assessed the proportion of lung disease in COVID-19 survivors by analyzing chest CT scans and pulmonary function tests. The findings suggest that pulmonary fibrosis and other sequelae are common in COVID-19 patients during follow-up. However, caution should be exercised in interpreting the estimates due to heterogeneity and differences in study populations.
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Pharmacology & Pharmacy
Evangelos Oikonomou et al.
Summary: In this study, the immediate, intermediate, and long-term effects of COVID-19 on endothelial function were assessed. The results showed that COVID-19 patients developed endothelial dysfunction, which improved over a 6-month follow-up but remained impaired compared to healthy controls. Further research is needed to investigate whether the chronic dysregulation of endothelial function following COVID-19 is associated with a residual risk for cardiovascular and thrombotic events.
VASCULAR PHARMACOLOGY
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Ibolya Rutkai et al.
Summary: COVID-19 infection can lead to neurological manifestations, and animal models can provide insights into the underlying mechanisms. In this study, neuroinflammation, microhemorrhages, and brain hypoxia were observed in SARS-CoV-2 infected non-human primates, even in those without severe respiratory disease. These findings are important for understanding the neuropathogenesis of SARS-CoV-2 infection and may help explain the neurological symptoms associated with long COVID.
NATURE COMMUNICATIONS
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Viet-Thi Tran et al.
Summary: About 10% of people infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) experience post COVID-19 disease. This study analyzed data from a French disease cohort and found that among patients symptomatic after 2 months, 85% still reported symptoms one year after their symptom onset. Symptoms showed different trends over time, with some decreasing, some remaining stable, and some increasing in prevalence. The study provides important insights into the natural history of post COVID-19 disease.
NATURE COMMUNICATIONS
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Daniel Ayoubkhani et al.
Summary: COVID-19 vaccination was associated with a decrease in the likelihood of long covid symptoms, and evidence suggested sustained improvement after a second dose, although longer follow-up is needed.
BMJ-BRITISH MEDICAL JOURNAL
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Review
Microbiology
Xiaoming Wu et al.
Summary: The intestinal tract is a major site of extrapulmonary infection in COVID-19, and viral infection and thrombosis can damage the gut-blood barrier, leading to intestinal injury and increased disease severity. Early prophylactic antithrombotic therapy can reduce these damages.
FRONTIERS IN MICROBIOLOGY
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LANCET RESPIRATORY MEDICINE
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Rachael A. Evans et al.
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LANCET RESPIRATORY MEDICINE
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Salma Charfeddine et al.
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Cardiac & Cardiovascular Systems
Rachel J. Skow et al.
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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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Letter
Critical Care Medicine
Emma Kooistra et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
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Clinical Neurology
Myoung Hwa Lee et al.
Summary: This autopsy study reveals the underlying mechanisms of brain microvascular pathology in patients with COVID-19, including vascular leakage, platelet aggregation, neuroinflammation, and neuronal injury, which are likely initiated by antibody-mediated cytotoxicity against brain endothelial cells.
Article
Cardiac & Cardiovascular Systems
Etheresia Pretorius et al.
Summary: Fibrin amyloid microclots and platelet hyperactivation in South African patients with Long COVID/PASC may be responsible for the persistent symptoms. Hypertension, high cholesterol levels, cardiovascular disease, and type 2 diabetes mellitus were found to be the most important comorbidities. The study highlights the need for further research on the pathophysiology and treatment of Long COVID/PASC.
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Multidisciplinary Sciences
Yonatan Woodbridge et al.
Summary: This study demonstrates that recent vaccination reduces Omicron viral load, but its effect wanes rapidly. In contrast, recovered COVID-19 individuals show a significantly slower waning rate. Therefore, a reassessment of future booster campaigns is needed.
NATURE COMMUNICATIONS
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Multidisciplinary Sciences
Karin Magnusson et al.
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Biochemistry & Molecular Biology
Charlotte Szewczykowski et al.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Medicine, General & Internal
Elena Azzolini et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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Medicine, General & Internal
Michela Antonelli et al.
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Multidisciplinary Sciences
Federico Armando et al.
Summary: This study compares virus spread and pathology in Syrian golden hamsters infected with different variants of SARS-CoV-2 and finds that the Omicron variant causes milder pathology.
NATURE COMMUNICATIONS
(2022)
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Cell Biology
Huiwen Zheng et al.
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Cardiac & Cardiovascular Systems
Lukas J. Motloch et al.
Summary: In COVID-19 survivors, early post-discharge prophylactic treatment with direct oral anticoagulation or dipyridamole can improve mid- and long-term cardiovascular events and all-cause mortality.
FRONTIERS IN CARDIOVASCULAR MEDICINE
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Letter
Cardiac & Cardiovascular Systems
Remy Martins-Goncalves et al.
CIRCULATION RESEARCH
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Biochemistry & Molecular Biology
Evan Xu et al.
Summary: Individuals with COVID-19 have an increased risk of developing a range of neurologic disorders at 12 months, even if they were not hospitalized during the acute phase of the infection.
Article
Hematology
Lize M. Grobbelaar et al.
Summary: The newer Omicron variants of SARS-CoV-2 are more transmissible but less virulent compared to earlier variants. Clotting parameters associated with Omicron variants are significantly raised but still lower than more severe variants like beta and delta.
SEMINARS IN THROMBOSIS AND HEMOSTASIS
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Immunology
Behdad Afzali et al.
Summary: Hyperactivation of the complement system is implicated in the pathology of COVID-19, with potential therapeutic benefits through complement inhibition. Latest research progress suggests targeting complement components for treatment may be beneficial in mitigating excessive inflammation and thrombosis in severe COVID-19 cases.
NATURE REVIEWS IMMUNOLOGY
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Peripheral Vascular Disease
Alexandros Rovas et al.
Summary: Our study found that COVID-19 patients have reduced microvascular density, slower red blood cell velocity, and glycocalyx damage. Elevated markers of endothelial dysfunction are associated with disease severity and can predict 60-day in-hospital mortality.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ilkay S. Idilman et al.
Summary: There is evidence of thrombotic events in COVID-19 patients, with a proportion showing lung and kidney perfusion abnormalities, suggesting systemic microangiopathy with micro-thrombosis. These findings may help in managing COVID-19 patients, including early indications of thromboprophylaxis and optimizing oxygenation strategies.
EUROPEAN RADIOLOGY
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Aristeidis H. Katsanos et al.
Summary: This study found that patients with SARS-CoV-2 infection have an increased risk of ischemic stroke and higher mortality rates.
ANNALS OF NEUROLOGY
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Biochemistry & Molecular Biology
Daniel Wendisch et al.
Summary: Analysis of pulmonary immune responses and lung pathology in patients with COVID-19 ARDS revealed an accumulation of profibrotic macrophages and similarities with macrophage populations in idiopathic pulmonary fibrosis. Exposure to SARS-CoV-2 induced a profibrotic phenotype in human monocytes, suggesting a mechanistic link between the virus and fibroproliferative ARDS.
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Respiratory System
Thomas Sonnweber et al.
Summary: A study found that some COVID-19 patients still experienced persistent symptoms and lung function impairment 100 days after the onset of the disease, but there was significant improvement in symptoms and cardiopulmonary status over time.
EUROPEAN RESPIRATORY JOURNAL
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Multidisciplinary Sciences
Christian Gaebler et al.
Summary: After infection with SARS-CoV-2, antibody levels against the spike protein decrease significantly, but the number of memory B cells remain unchanged, indicating an evolving humoral response at 6.2 months after infection.
Letter
Medicine, General & Internal
Daniel P. Perl et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Physiology
Camilla Ferrari et al.
Summary: The history of Alzheimer's disease dates back to 1907, but it wasn't until the end of the century that the components of pathological hallmarks and genetic subtypes were identified, leading to the first pathogenic hypothesis. Advances in biomarkers and technology have shifted the concept of AD from a static view to a biological entity that can manifest in various ways. Research shows that AD is heterogeneous in terms of amyloid composition, tau distribution, clinical symptoms, and genetic background, making it difficult to explain with a single pathological process.
PHYSIOLOGICAL REVIEWS
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Review
Critical Care Medicine
Ranju T. Dhawan et al.
Summary: COVID-19 is associated with pulmonary thrombosis and thromboembolism, potentially leading to pulmonary fibrotic damage and long-term consequences. A proactive follow-up strategy is needed to evaluate residual clot burden, small vessel injury, and potential hemodynamic sequelae. A nuanced and physiological approach to follow-up imaging is crucial for informing therapeutic strategies in case of clinically significant pulmonary vascular sequelae.
LANCET RESPIRATORY MEDICINE
(2021)
Article
Hematology
Annabelle Dupont et al.
Summary: The study investigated the association between endothelial damage and immune dysregulation with organ failure, thrombus formation, and death in 82 patients with COVID-19, finding a direct role of endotheliopathy in organ failure and an association between dysregulated immune response and respiratory failure, liver injury, and death. Thrombi from COVID-19 patients on extracorporeal membrane oxygenation showed increased neutrophil accumulation and neutrophil extracellular traps compared to non-COVID-19 thrombi.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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Respiratory System
Michael F. Morris et al.
Summary: Evidence suggests that a decrease in BV5% on chest CT scans may predict adverse clinical outcomes in COVID-19 patients. A BV5% threshold below 25% was associated with increased odds ratios for mortality, intubation, and the composite of mortality or intubation, indicating its potential as a novel biomarker for predicting outcomes in these patients.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Cell Biology
Felice D'Agnillo et al.
Summary: This study identified significant pulmonary pathological features in fatal COVID-19 cases, including progressive diffuse alveolar damage, excessive thrombosis, and delayed pulmonary tissue and vascular remodeling. Acute damage at the alveolar-capillary barrier was characterized by loss of surfactant protein expression and injury to various types of cells, such as alveolar epithelial cells and endothelial cells. These findings provide insights into potential therapeutic targets for treating SARS-CoV-2 infection-induced respiratory distress.
SCIENCE TRANSLATIONAL MEDICINE
(2021)
Article
Virology
Richard Vollenberg et al.
Summary: This study identifies signs of endothelial damage in convalescent COVID-19 patients after mild disease progression without hospitalization, consistent with studies showing evidence of persistent endothelial damage after severe or critical disease progression. Further research should investigate endothelial damage in convalescent COVID-19 patients.
Article
Multidisciplinary Sciences
Yan Xie et al.
Summary: The study analyzed data from the US Department of Veterans Affairs healthcare databases to estimate the burden of Post-Acute Sequelae of SARS-CoV-2 infection (PASC), finding approximately 73.43 PASC cases per 1000 persons at 6 months. The burden of PASC varied by demographic groups and baseline health status, with more severe acute infection leading to higher burden. The study highlights the substantial burden of PASC and the importance of considering different population groups when planning healthcare strategies.
NATURE COMMUNICATIONS
(2021)
News Item
Medicine, General & Internal
Elisabeth Mahase
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Clinical Neurology
Kiran T. Thakur et al.
Summary: Many patients with SARS-CoV-2 infection exhibit neurological signs and symptoms, but autopsy results show that most brains have low levels of detectable virus and it does not correlate with the histopathological alterations.
Letter
Cardiac & Cardiovascular Systems
Yuyang Lei et al.
CIRCULATION RESEARCH
(2021)
Article
Gastroenterology & Hepatology
Markus F. Neurath et al.
Article
Immunology
I. S. Cheon et al.
Summary: Through high-dimensional characterization of the pathophysiological and immune traits of aged COVID-19 convalescents, it was found that chronic lung impairment was accompanied by persistent respiratory immune alterations, with functional SARS-CoV-2-specific memory T and B cells enriched at the site of infection. Dysregulated respiratory CD8(+) T cell responses were associated with impaired lung function after acute COVID-19, with potential pathogenic subsets contributing to persistent tissue conditions.
SCIENCE IMMUNOLOGY
(2021)
Editorial Material
Endocrinology & Metabolism
Kamlesh Khunti et al.
Summary: Cardiometabolic conditions, like type 1 and type 2 diabetes mellitus, are linked to severe COVID-19 and long COVID. Interventions targeting multiple risk factors, along with the use of novel glucose-lowering agents, are recommended for managing long COVID in people.
NATURE REVIEWS ENDOCRINOLOGY
(2021)
Article
Biology
Florence W. J. Chioh et al.
Summary: The impact of COVID-19 on vascular health of recovered patients is significant, with elevated levels of circulating endothelial cells indicating vascular injury. The presence of proinflammatory and activated T lymphocyte-associated cytokines suggests cytokine-driven endothelial dysfunction. Effector T cells were more frequent in COVID-19 convalescents, pointing to a possible cytotoxic effector cell targeting of activated endothelial cells.
Review
Peripheral Vascular Disease
David M. Smadja et al.
Summary: COVID-19 caused by SARS-CoV-2 is a systemic disease associated with vascular inflammation and endothelial injury, which can lead to ARDS and hypercoagulation. Besides pro-inflammatory cytokines, endothelial dysfunction can also cause hypercoagulation, thrombosis and pathological angiogenesis.
Article
Hematology
Dimitrios Giannis et al.
Summary: Thromboembolic events and mortality from subclinical thrombotic events frequently occur in COVID-19 inpatients. Postdischarge VTE, ATE, and ACM are common, with advanced age and cardiovascular risk factors increasing the risk. Postdischarge anticoagulation can significantly reduce the risk by 46%.
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Cardiac & Cardiovascular Systems
Vaia Lambadiari et al.
Summary: Findings from the study suggest that COVID-19 infection may result in endothelial and vascular dysfunction four months after infection, manifesting in altered arterial stiffness, coronary and myocardial function, and changes in markers related to endothelial health.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
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Immunology
Marius Schwabenland et al.
Summary: The study found profound neuroinflammation in COVID-19 patients, with activation of innate and adaptive immune cells. These pathological changes are associated with systemic inflammation and disturbed hemostasis, suggesting potential therapeutic strategies.
Article
Dermatology
Lisa M. Arkin et al.
Summary: Despite the large number of patients with pandemic-associated pernio, establishing a causal link to SARS-CoV-2 remains a challenge. Pathophysiological studies suggest that some children with pernio may have abnormalities in IFN-1 immunity, while excessive immune responses to SARS-CoV-2 are seen in the skin of pernio patients.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2021)
Article
Urology & Nephrology
Benjamin Bowe et al.
Summary: The study showed that survivors of COVID-19 had an increased risk of kidney outcomes in the post-acute phase of the disease, indicating the importance of paying attention to kidney disease in long-term COVID-19 care.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Hematology
Helen Fogarty et al.
Summary: The study found that endothelial cell activation may persist in convalescent COVID-19 patients and may contribute to the pathogenesis of long COVID. This sustained endotheliopathy was more common in older, comorbid patients, and those requiring hospitalization, indicating a potential link between endothelial dysfunction and long-term COVID symptoms.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2021)
Article
Medicine, General & Internal
Thomas M Drake et al.
Article
Biochemistry & Molecular Biology
Bjorn Blomberg et al.
Summary: An analysis of patients with SARS-CoV-2 infections in Bergen, Norway, revealed that a high proportion of patients experienced long-term COVID symptoms at 6 months, even though they were relatively young and had only mild to moderate acute COVID-19 symptoms. This highlights the significance of infection control measures, such as vaccination.
Review
Biotechnology & Applied Microbiology
Ilse S. Daehn et al.
Summary: This review discusses strategies to target components of the glomerular filtration barrier (GFB) to improve kidney function, focusing on controlling mitochondrial function and the actin-myosin contractile machinery. Developments in therapies targeting the GFB offer potential for new interventions in kidney diseases.
NATURE REVIEWS DRUG DISCOVERY
(2021)
Editorial Material
Urology & Nephrology
Sachin Yende et al.
Summary: Kidney involvement is common in acute SARS-CoV-2 infection, with subclinical inflammation and injury potentially leading to chronic kidney disease. Further research is crucial to understanding these long-term consequences and finding interventions to mitigate them.
NATURE REVIEWS NEPHROLOGY
(2021)
Review
Urology & Nephrology
Matthieu Legrand et al.
Summary: Acute kidney injury (AKI) is a common complication of COVID-19, and potential mechanisms for COVID-19-associated AKI include systemic haemodynamic instability, local immune cell infiltration, and endothelial injury, which may lead to impaired kidney function.
NATURE REVIEWS NEPHROLOGY
(2021)
Article
Medicine, General & Internal
Sue Pavord et al.
Summary: Phenotypes of VITT were defined in 220 patients in the United Kingdom who presented a median of 14 days after the first ChAdOx1 nCoV-19 vaccination. Half had cerebral venous sinus thrombosis, a third of whom also had intracranial hemorrhage. Mortality was 22%. Intravenous immune globulin may reverse VITT.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Immunology
Fengming Liu et al.
Summary: This study found that SARS-CoV-2 may directly infect mature vascular endothelial cells in vivo and ex vivo, potentially contributing to cardiovascular complications in SARS-CoV-2 infection, including multiple organ failure.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Tessa J. Barrett et al.
Summary: The study reveals an inflammatory hypercoagulable state between platelets and endothelial cells in COVID-19, with platelet-released factors promoting endotheliopathy. S100A8, S100A9, and their protein product MRP8/14 are enriched in COVID-19 platelets and contribute significantly to poor clinical outcomes. Targeting platelet P2Y(12) appears to be a promising strategy for reducing proinflammatory platelet-endothelial interactions in COVID-19.
Article
Critical Care Medicine
Meint Volbeda et al.
Summary: This study analyzed postmortem kidney biopsies from COVID-19 and bacterial sepsis patients, revealing distinct histopathological features and gene expression patterns in COVID-19 patients with more severe ATN and microvascular thrombosis. Furthermore, decreased levels of ACE2 mRNA and angiopoietin-1, as well as disrupted microvascular flow, were observed in COVID-19 patients, suggesting unique pathophysiological mechanisms of AKI in COVID-19.
Article
Immunology
Aldo Bonaventura et al.
Summary: The authors suggest that SARS-CoV-2 infection induces a prothrombotic state and dysregulated immunothrombosis, leading to severe manifestations of COVID-19. They also discuss potential antithrombotic and immunomodulating drugs for treating COVID-19 patients, aiming to reduce the acute and long-term consequences of the disease by targeting immunothrombosis.
NATURE REVIEWS IMMUNOLOGY
(2021)
Letter
Respiratory System
Laura Michalick et al.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Review
Gastroenterology & Hepatology
Shahnaz Sultan et al.
Article
Gastroenterology & Hepatology
Tao Zuo et al.
Article
Gastroenterology & Hepatology
Ka Shing Cheung et al.
Letter
Hematology
Marisa Dolhnikoff et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2020)
Review
Urology & Nephrology
Marina Noris et al.
KIDNEY INTERNATIONAL
(2020)
Article
Urology & Nephrology
Hua Su et al.
KIDNEY INTERNATIONAL
(2020)
Letter
Medicine, General & Internal
Zsuzsanna Varga et al.
Article
Medicine, General & Internal
Maximilian Ackermann et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Article
Medicine, General & Internal
Victor G. Puelles et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Editorial Material
Gastroenterology & Hepatology
Lorenzo Norsa et al.
Article
Hematology
George Goshua et al.
LANCET HAEMATOLOGY
(2020)
Letter
Medicine, General & Internal
Angelo Carfi et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2020)
Article
Urology & Nephrology
Purva Sharma et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2020)
Article
Immunology
Fengyu Hu et al.
CELLULAR & MOLECULAR IMMUNOLOGY
(2020)
Article
Neurosciences
Tetyana P. Buzhdygan et al.
NEUROBIOLOGY OF DISEASE
(2020)
Review
Physiology
Nina Wettschureck et al.
PHYSIOLOGICAL REVIEWS
(2019)
Review
Hematology
T. Iba et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2019)
Review
Urology & Nephrology
Noemie Jourde-Chiche et al.
NATURE REVIEWS NEPHROLOGY
(2019)
Review
Physiology
Melanie D. Sweeney et al.
PHYSIOLOGICAL REVIEWS
(2019)
Review
Pharmacology & Pharmacy
Michelle A. Erickson et al.
PHARMACOLOGICAL REVIEWS
(2018)
Review
Immunology
Ilaria Spadoni et al.
NATURE REVIEWS IMMUNOLOGY
(2017)
Article
Hematology
Muhua Cao et al.
Review
Immunology
Britta Engelhardt et al.
Review
Multidisciplinary Sciences
Christoph A. Thaiss et al.
Article
Hematology
Zhangxiu He et al.
THROMBOSIS AND HAEMOSTASIS
(2016)
Review
Physiology
Henri H. Versteeg et al.
PHYSIOLOGICAL REVIEWS
(2013)
Article
Neurosciences
G. Joshi et al.
Review
Cardiac & Cardiovascular Systems
William C. Aird
CIRCULATION RESEARCH
(2007)
Article
Hematology
JL Shi et al.
