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Mechanisms of the Antimicrobial Activities of Graphene Materials

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 138, Issue 7, Pages 2064-2077

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jacs.5b11411

Keywords

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Funding

  1. National Natural Science Foundation of China [81572079, 81371899]
  2. National Key Basic Research Support Foundation [2015CB755400]
  3. Science Fund for Distinguished Young Scholars of Chongqing [CSTC2014JCYJJQ10007]
  4. Natural Science Foundation of Chongqing, China [CSTC2013JJB10012]
  5. Twelfth Five-Year Plan of PLA, China [CWS13C046]

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A thorough understanding of the antimicrobial mechanisms of graphene materials (GMs) is critical to the manipulation of highly efficient antimicrobial nanomaterials for future biomedical applications. Here we review the most recent studies of GM-mediated antimicrobial properties. This review covers the physicochemical properties of GMs, experimental surroundings, and selected microorganisms as well as the interaction between GMs and selected microorganisms to explore controversial antimicrobial activities. Finally, we rationally analyze the strengths and weaknesses of the proposed mechanisms and provide new insights into the remaining challenges and perspectives for future studies.

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