4.3 Article

A novel array-type microdroplet parallel-generation device

Journal

ANALYTICAL SCIENCES
Volume -, Issue -, Pages -

Publisher

SPRINGERNATURE
DOI: 10.1007/s44211-023-00378-6

Keywords

Microdispensing; Non-contact printing; Microdroplet arrays; Parallel transfer printing microarray; Electromagnet actuation

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In this study, an innovative design of a new array microdroplet parallel-generation device based on fluid inertial force using a capillary glass needle is proposed. The device, using an electromagnetic actuator as the power source, consists of a 9-channel parallel array of glass needles that independently feed different solutions to avoid cross-contamination. The study investigates the homogeneity of droplet arrays, stability of the device, and the factors influencing microdroplet size, and develops a prediction model for droplet size, demonstrating the potential of the device for high precision and low-volume microdroplet-array generation.
In this study, the innovative design of a new array microdroplet parallel-generation device is proposed based on the principle of fluid inertial force using a capillary glass needle. The entire device used an electromagnetic actuator as the power source. It was designed as a 9-channel parallel array of glass needles. All glass needles feed independently, allowing different solutions to be sprayed simultaneously while effectively avoiding cross-contamination. We achieved non-contact parallel precision dispensing of nanoliter-sized microdroplet arrays using a relatively simple method. In this study, we first investigated the homogeneity of the generated droplet arrays and the stability of the device over long periods of operation. Then, the influence of the driving-voltage amplitude of the electromagnet and nozzle diameter on microdroplet generation was analyzed. Finally, a prediction model for the droplet size was developed using regression analysis to investigate the on-demand generation of droplets. In summary, the device designed in this study had a novel design, low cost, and modular assembly. It has excellent potential for applications in high precision and low-volume microdroplet-array generation.

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