Journal
ANALYTICA CHIMICA ACTA
Volume 1245, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.aca.2023.340829
Keywords
Screen printed electrode; Live-cell assay; Interface engineering; Functional ink; Nanozyme; Carbon nanofiber
Categories
Ask authors/readers for more resources
A unique carbon-based material comprising Pt-CuO nanocrystal interfacially anchored on functionalized carbon nanofiber (Pt-CuO@FCNF) was developed for ultrasensitive detection of cell-released H2O2 using a screen printed electrode (SPE). Pt-CuO@FCNF showed a wide linear response range, low detection limit, fast response time, and good selectivity.
Screen printed electrode (SPE) on carbon-based inks exhibits promising applications in biosensing, environment protection and food safety. We report here a unique carbon-based material comprising Pt-CuO nanocrystal interfacially anchored on functionalized carbon nanofiber (Pt-CuO@FCNF) and its functional ink to build SPE for ultrasensitive detection of cell released H2O2. Pt-CuO@FCNF is fabricated using a one-pot and mass production method through direct pyrolysis of Pt and CuO precursors together with FCNF. FCNF with 1-D structure and high electrical conductivity can interfically anchor Pt-CuO nanocrystal, which synergically promotes rich active site and catalytic activity towards H2O2. Pt-CuO@FCNF exhibits a wide linear response of 0.4 mu M-11 mM, a low detection limit of 17 nM, a fast response time of 1.0 s, and good selectivity. Eventually, Pt-CuO@FCNF SPE realizes real-time and ultrasensitive qualification of H2O2 released from both normal and cancer cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available