4.8 Article

Pd-Catalyzed C(sp3)-H Functionalization/Carbenoid Insertion: All-Carbon Quaternary Centers via Multiple C-C Bond Formation

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 138, Issue 20, Pages 6384-6387

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jacs.6b02867

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Funding

  1. ICIQ
  2. European Research Council [ERC-277883]
  3. MINECO [CTQ2015-65496-R, SEV-2013-0319]
  4. Cellex Foundation
  5. COFUND
  6. ICREA Funding Source: Custom

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A Pd-catalyzed C(sp(3))-H functionalization/carbenoid insertion is described. The method allows for the rapid synthesis of bicyclic frameworks, generating all-carbon quaternary centers via multiple C-C bond formations in a straightforward manner.

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