Related references
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Article
Immunology
Mark W. Tenforde et al.
Summary: Based on household survey data and reported SARS-CoV-2 cases, it is estimated that at least 3.0-5.0 million US adults, or 1.2%-1.9% of the US adult population, had activity-limiting post-COVID conditions of >= 1 month's duration on November 1, 2021. The prevalence was higher in females than males.
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Summary: This study examined the health status, persistent symptoms, and effort tolerance approximately 1 year after COVID-19 infection and found that post-acute COVID-19 sequelae (PASC) are very common during this time period and severe enough to impact daily exercise tolerance. PASC symptoms are widely distributed, not limited to a specific patient group, and unrelated to age.
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Summary: Phetsouphanh and colleagues found that individuals with long COVID exhibit persistent activation of the immune system even 8 months after infection. They also identified a set of analytes associated with long COVID, suggesting potential opportunities for prevention and treatment.
Review
Immunology
Saurabh Mehandru et al.
Summary: This review examines the underlying pathophysiological mechanisms of post-COVID-19 syndromes, including persistent inflammation, induced autoimmunity, and putative viral reservoirs. The disease is called 'long-haul COVID' or 'post-COVID-19 syndrome', and clinical symptoms include fatigue, dyspnea, and neuropsychiatric syndromes.
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Multidisciplinary Sciences
Miriam Merad et al.
Summary: Considerable research effort has been focused on deciphering the immune response to SARS-CoV-2 infections and understanding the pathophysiology of COVID-19, including Long Covid syndrome. The hope is that knowledge gained from this research will be applied to studies of inflammatory processes in critical and chronic illnesses in the future.
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Multidisciplinary Sciences
Ellen J. Thompson et al.
Summary: The frequency and risk factors of long COVID in community-based individuals are unclear. A study analyzing data from 10 UK population-based studies and electronic health records found wide variation in the frequency of long COVID between studies, but identified some consistent risk factors.
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Immunology
Monica Fung et al.
Summary: The COVID-19 pandemic caused by SARS-CoV-2 has led to significant morbidity and mortality globally. The impact of the disease on immunosuppressed patients, such as cancer patients and transplant recipients, remains unclear. Further research is needed to determine the risk of COVID-19 severity and death in immunocompromised patients.
CLINICAL INFECTIOUS DISEASES
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Nathanael R. Fillmore et al.
Summary: The study found that COVID-19 infection rates and outcomes in cancer patients are influenced by various factors such as race, cancer type, age, and comorbidities. The presence of cancer itself affects susceptibility and eventual outcomes. However, race and recent treatments (including immunotherapy) do not impact outcomes of COVID-19.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
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Petter Brodin
Summary: The severity of COVID-19 varies by sex and age, and is linked to comorbidities. Differences in immune reactions may go some way to explain this.
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Medicine, General & Internal
Destin Groff et al.
Summary: This systematic review found that more than half of COVID-19 survivors experienced PASC 6 months after recovery, with the most common effects being functional mobility impairments, pulmonary abnormalities, and mental health disorders.
Article
Multidisciplinary Sciences
Ziyad Al-Aly et al.
Summary: This study comprehensively describes the post-acute sequelae of COVID-19 using national healthcare databases, finding increased risk of death and use of health resources beyond the first 30 days of illness, as well as incident sequelae in various organ systems, increased use of therapeutic agents, and evidence of laboratory abnormalities. The findings show a risk gradient according to the severity of acute COVID-19 infection and highlight the burden of health loss experienced by patients who survive the acute phase.
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
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Biochemistry & Molecular Biology
Chen Chai et al.
Summary: This study found that COVID-19 patients with cancer have significantly higher 1-year mortality rates compared to non-cancer patients, but the long-term mortality rate of surviving cancer COVID-19 patients is similar to that of cancer patients. Different tumor subtypes have different effects on COVID-19 outcomes.
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JOURNAL OF MOLECULAR MEDICINE-JMM
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ANNALS OF ONCOLOGY
(2012)
Review
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