4.6 Article

Arsenic exposure and pruritus: Evidence from observational, interventional, and mendelian randomization studies

Related references

Note: Only part of the references are listed.
Letter Dermatology

Association of psoriasis with risk of COVID-19: A 2-sample Mendelian randomization study

Xiaoyu Gu et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Review Endocrinology & Metabolism

Is Arsenic Exposure a Risk Factor for Metabolic Syndrome? A Review of the Potential Mechanisms

Pablo Panico et al.

Summary: Exposure to arsenic in drinking water is a global health problem associated with an increased risk of developing metabolic diseases. Metabolic syndrome is a complex pathology that results from the interaction between environmental and genetic factors, and is linked to an increased risk of developing type 2 diabetes, cardiovascular diseases, and cancer.

FRONTIERS IN ENDOCRINOLOGY (2022)

Article Engineering, Environmental

Microcystin-LR Combined with Cadmium Exposures and the Risk of Chronic Kidney Disease: A Case-Control Study in Central China

Shuidong Feng et al.

Summary: This study found that exposure to microcystin-LR was independently associated with chronic kidney disease (CKD) risk and had a synergistic relationship with cadmium. The exposure to microcystin-LR and cadmium was dose-dependently associated with CKD risk.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2022)

Article Dermatology

Role of kappa-opioid and mu-opioid receptors in pruritus: Peripheral and central itch circuits

Brian S. Kim et al.

Summary: Modern genetic approaches have identified new neural pathways specific to itch, providing potential for drug development. Opioid receptors play a role in modulating itch, but the precise mechanisms are still being investigated. Nevertheless, several drugs have shown efficacy in clinical trials by targeting opioid receptor signaling.

EXPERIMENTAL DERMATOLOGY (2022)

Review Biochemistry & Molecular Biology

Roles of β-Endorphin in Stress, Behavior, Neuroinflammation, and Brain Energy Metabolism

Alexander Pilozzi et al.

Summary: Beta-endorphins are peptides with diverse effects throughout the body, primarily binding to mu opioid receptors for analgesic effects, and also influencing reward-centric and homeostasis-restoring behaviors. Their roles in psychiatric and neurodegenerative disorders make them a target of interest in research.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Environmental Sciences

Association of multi-metals exposure with intelligence quotient score of children: A prospective cohort study

Minxue Shen et al.

Summary: The study evaluated the joint effects of lead (Pb), manganese (Mn), antimony (Sb), tin (Sn), and titanium (Ti) coexposure on children's IQ scores. Results showed that multi-metal exposures were associated with a decline in children's IQ scores, with interactions between certain metals influencing IQ levels.

ENVIRONMENT INTERNATIONAL (2021)

Article Neurosciences

Association of arsenic exposure and cognitive impairment: A population-based cross-sectional study in China

Xin Wang et al.

Summary: The study found that both hair arsenic concentrations and arsenicosis prevalence were significantly higher in the cognitive-impaired group compared to the cognitive-normal group. Furthermore, the distance from the Realgar Plant was positively correlated with MMSE scores and negatively correlated with the prevalence of cognitive impairment. Hair arsenic concentrations were negatively correlated with MMSE scores.

NEUROTOXICOLOGY (2021)

Review Biochemistry & Molecular Biology

Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions

Manisha Thakur et al.

Summary: Arsenic is a significant environmental toxicant that impacts human health. Exposure to arsenic can lead to various health issues such as cancer, coronary disease, and neurological disorders, with inorganic arsenic exhibiting higher toxicity levels. Long-term exposure to arsenic may result in neurobehavioral effects, which could have detrimental impacts in later stages of life.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Immunology

Autoreactive T cells and their role in atopic dermatitis

Tina De Bruyn Carlier et al.

Summary: Atopic dermatitis is a chronic inflammatory skin disease that develops in early childhood and is associated with food allergy, with immune reactions potentially leading to autoimmune processes. The exact mechanisms of IgE-mediated autoimmunity and self-reactive T cells in the pathophysiology of AD are still unclear.

JOURNAL OF AUTOIMMUNITY (2021)

Article Dermatology

Itch and Mental Health in Dermatological Patients across Europe: A Cross-Sectional Study in 13 Countries

Florence J. Dalgard et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2020)

Article Pharmacology & Pharmacy

The Neuropeptide Y Y2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y2 Activation Reduces Histaminergic and IL-31-Itch

Haisha Ma et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)

Review Neurosciences

Endogenous and Exogenous Opioids in Pain

Gregory Corder et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)

Article Medicine, Research & Experimental

Elevated endogenous opioids in obstructive jaundice: The possible skin mechanisms

Xiaoqian Li et al.

MEDICAL HYPOTHESES (2018)

Review Immunology

Skin neurogenic inflammation

Jae Eun Choi et al.

SEMINARS IN IMMUNOPATHOLOGY (2018)

Article Environmental Sciences

Prevalence and associated demographic characteristics of exposure to multiple metals and their species in human populations: The United States NHANES, 2007-2012

Youn K. Shim et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2017)

Article Dermatology

Update on the cutaneous neurobiology of pruritus

U. Raap et al.

HAUTARZT (2016)

Article Environmental Sciences

Urinary Metals and Heart Rate Variability: A Cross-Sectional Study of Urban Adults in Wuhan, China

Wei Feng et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2015)

Article Medicine, Research & Experimental

Neural peptidase endothelin-converting enzyme 1-regulates endothelin induced pruritus

Makiko Kido-Nakahara et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Review Medicine, General & Internal

Pruritus in the Older Patient A Clinical Review

Timothy G. Berger et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

Article Chemistry, Medicinal

SAR and biological evaluation of 3-azabicyclo[3.1.0]hexane derivatives as μ opioid ligands

Graham Lunn et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Dermatology

Evaluation of epidermal nerve density and opioid receptor levels in psoriatic itch

Kenichi Taneda et al.

BRITISH JOURNAL OF DERMATOLOGY (2011)

Article Substance Abuse

A pharmacogenetic model of naltrexone-induced attenuation of alcohol consumption in rhesus monkeys

Eric J. Vallender et al.

DRUG AND ALCOHOL DEPENDENCE (2010)

Article Pharmacology & Pharmacy

Involvement of peripheral mu opioid receptors in scratching behavior in mice

Atsuki Yamamoto et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2010)

Review Dermatology

Antipruritic treatment with systemic mu-opioid receptor antagonists: A review

Ngoc Quan Phan et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2010)

Review Dermatology

Epidemiology of Itch: Adding to the Burden of Skin Morbidity

Elke Weisshaar et al.

ACTA DERMATO-VENEREOLOGICA (2009)

Review Environmental Sciences

BIOMONITORING FOR ENVIRONMENTAL EXPOSURES TO ARSENIC

Kenneth Orloff et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2009)

Article Medicine, General & Internal

Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review

Ulrike Durrant-Finn et al.

WIENER MEDIZINISCHE WOCHENSCHRIFT (2009)

Article Critical Care Medicine

Naltrexone for the management of post-burn pruritus: A preliminary report

L. LaSalle et al.

BURNS (2008)

Article Dermatology

Possible roles of epidermal opioid systems in pruritus of atopic dermatitis

Mitsutoshi Tominaga et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)

Review Neurosciences

The neurobiology of itch

Akihiko Ikoma et al.

NATURE REVIEWS NEUROSCIENCE (2006)

Article Medical Laboratory Technology

Caveats in hair analysis in chronic arsenic poisoning

JT Hindmarsh

CLINICAL BIOCHEMISTRY (2002)