Visible-Light-Driven Copper-Catalyzed Synthesis of Sulfonamides from Aryl-N2BF4 through One-pot Tricomponent Reaction

A method for preparing sulfonamides using visible light is described. In this approach, an aryl diazo tetrafluoroborate salt, 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO), and amino benzoate as substrates, CuBr2 as a catalyst, and 3-methyl-3-pentanol as an additive were employed for a one-pot multicomponent reaction to provide sulfonamides under mild reaction conditions. A variety of aryl diazo tetrafluoroborate salts and O-benzoyl hydroxylamines were tolerated in this process to provide products with yields up to 96%.

Automated summary

A method for preparing sulfonamides using visible light is described in this study. The method involves the use of aryl diazo tetrafluoroborate salt, 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO), and amino benzoate as substrates, with CuBr2 as a catalyst and 3-methyl-3-pentanol as an additive. This one-pot multicomponent reaction provides sulfonamides under mild conditions, yielding products with up to 96% yield.