☆ 4.8 Article

Engineered Bicomponent Adhesives with Instantaneous and Superior Adhesion Performance for Wound Sealing and Healing Applications

ADVANCED FUNCTIONAL MATERIALS (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

Biomimetic Natural Biopolymer-Based Wet-Tissue Adhesive for Tough Adhesion, Seamless Sealed, Emergency/Nonpressing Hemostasis, and Promoted Wound Healing

Wen Yang et al.

Summary: In this study, a robust wet tissue adhesive based on collagen and starch materials is designed, which shows strong wet tissue adhesiveness, high sealing performance, fast self-healing ability, excellent injectability, and shape adaptability. The adhesive exhibits better hemostatic efficiency than fibrin glue in rat models and accelerates wound healing and functional recovery.

ADVANCED FUNCTIONAL MATERIALS (2023)

Add to Collection

Review Chemistry, Multidisciplinary

Protein-Based Biological Materials: Molecular Design and Artificial Production

Ali Miserez et al.

Summary: Materials produced from natural biopolymers provide a sustainable alternative to synthetic polymers, with harmless degradation products. This review explores the chemical design and biofabrication of protein-based materials, including their primary sequences and structural levels, as well as their mechanical response. The latest research on artificially producing protein-based materials using biotechnology and synthetic biology is also discussed.

CHEMICAL REVIEWS (2023)

Add to Collection

Article Chemistry, Multidisciplinary

Injectable Double-Crosslinked Adhesive Hydrogels with High Mechanical Resilience and Effective Energy Dissipation for Joint Wound Treatment

Kai Chen et al.

Summary: This article presents a polymer hydrogel with strong moist adhesion and dynamic tissue adhesion properties, suitable for joint wound closure and healing. The enhancement of moist adhesion through a stable crosslinked network and multiple hydrogen bonds in the hydrogel resulted in excellent adhesive performance in experiments.

ADVANCED FUNCTIONAL MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

An Engineered Protein-Au Bioplaster for Efficient Skin Tumor Therapy

Zheng Wei et al.

Summary: A novel bifunctional protein-based photothermal bioplaster (PPTB) has been developed for the therapy of melanoma and skin tissue regeneration. The PPTB bioagent has good biocompatibility, controllable adhesion performance, and high photothermal performance, enabling convenient removal of skin tumors.

ADVANCED MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Biosynthetic Structural Proteins with Super Plasticity, Extraordinary Mechanical Performance, Biodegradability, Biocompatibility and Information Storage Ability

Juanjuan Su et al.

Summary: The study introduces a simple and environmentally friendly approach to fabricate protein-based plastics using structural proteins as building blocks. These bioplastics possess strong mechanical performance, adjustable physicochemical properties, biocompatibility, and biodegradability. The study also demonstrates the potential of the bioplastics in high density information storage and hemostatic applications.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Bioengineered Protein-based Adhesives for Biomedical Applications

Jing Sun et al.

Summary: Protein-based adhesives have been explored for biomedical applications due to their strong adhesion performance and excellent biocompatibility. Genetic engineering has enabled these adhesives to maintain underwater adhesion property as well as biocompatibility. Recent advances in this area include elastin-like polypeptide-based adhesives, mussel foot protein-based adhesives, and other protein sources like spider silk spidroin and suckerin. Bioengineered protein-based adhesives show promise for future development in biomedical applications.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Emerging Biopolymer-Based Bioadhesives

Jinghang Li et al.

Summary: The development of bioadhesives using naturally derived biopolymers has addressed challenges and made significant progress, leading to their wide applications in healthcare and biomedical fields.

MACROMOLECULAR BIOSCIENCE (2022)

Add to Collection

Review Chemistry, Physical

Engineered protein nanodrug as an emerging therapeutic tool

Yuanxin Li et al.

Summary: This review summarizes the recent progress in the fabrication and application of therapeutic proteins, including strategies for improving therapeutic efficacy through bioengineering and nanoassembly, and the diverse applications of therapeutic proteins as growth factors, nanovaccines, antibody-based drugs, bioimaging molecules, and cytokine receptor antagonists.

NANO RESEARCH (2022)

Add to Collection

Article Multidisciplinary Sciences

Gelation of highly entangled hydrophobic macromolecular fluid for ultrastrong underwater in situ fast tissue adhesion

Yuqing Liu et al.

Summary: This study proposes a hydrophobic adhesive UIHA that can perform in the presence of body fluids. The gelation of the hydrophobic fluid enables strong bonding to tissues and exceptional water resistance.

SCIENCE ADVANCES (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Molecular Engineered Crown-Ether-Protein with Strong Adhesion over a Wide Temperature Range from-196 to 200 °C

Kelu Zhao et al.

Summary: In this study, a temperature-resistant adhesive, crown-ether-protein (CEP), is developed by harnessing synergistic host-guest molecular interactions between crown ether and protein. The CEP adhesive demonstrates ultrahigh shearing adhesion strength over a wide temperature range, surpassing other supramolecular or polymeric adhesives.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Engineered Hemostatic Biomaterials for Sealing Wounds

Hossein Montazerian et al.

Summary: Hemostatic biomaterials have great potential in wound control, particularly for uncontrolled bleeding associated with damaged tissues, traumatic wounds, and surgical incisions. Current research focuses on enhancing the hemostatic properties of bioactive materials through triggering the coagulation cascade, using biocompatible and biodegradable materials for rapid blood coagulation, and developing tough bioadhesives for efficient incision sealing.

CHEMICAL REVIEWS (2022)

Add to Collection

Article Chemistry, Physical

Biological composite fibers with extraordinary mechanical strength and toughness mediated by multiple intermolecular interacting networks

Sikang Wan et al.

Summary: This study presents a versatile strategy for the fabrication of protein-saccharide composite fibers through protein-initiated double interacting networks. The introduction of lysine-rich bioengineered proteins significantly enhances the mechanical properties of the composite fibers through multiple cross-linking interactions.

NANO RESEARCH (2022)

Add to Collection

Article Chemistry, Multidisciplinary

An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing

Shaoquan Bian et al.

Summary: The study successfully developed an injectable hydrogel with rapid adhesion and anti-swelling properties. The hydrogel can quickly adhere to wet tissues and maintains its volume stability during degradation. It demonstrates fast hemostasis in various bleeding models and has good biocompatibility with low risk of hemolysis.

ADVANCED FUNCTIONAL MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Biosynthetic and Unfolded Protein Nanocarriers for Chemotherapeutic Drugs in Oral Cancers: Improved Bioavailability and Safety of Chemotherapeutics

Juanjuan Su et al.

Summary: A new type of biosynthetic and unfolded protein nanocarrier has been developed, which efficiently loads and delivers a variety of chemotherapeutic agents for oral squamous cell carcinoma (OSCC) therapy. This versatile formulation strategy improves efficacy, bioavailability, and safety of chemotherapeutics while mitigating off-target side effects.

ADVANCED FUNCTIONAL MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Bioengineered Protein Fibers with Anti-Freezing Mechanical Behaviors

Peng Zhang et al.

Summary: This study reports the creation of freezing tolerant protein fibers with favorable ice-phobic capacity and cryogenic mechanical performance through genetic engineering. These fibers, composed of chimeric recombinant proteins, exhibit excellent ice recrystallization inhibition activity and maintain remarkable mechanical properties and stability in subzero environments.

ADVANCED FUNCTIONAL MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Molecularly Engineered Protein Glues with Superior Adhesion Performance

Zili Wang et al.

Summary: In this study, a new generation of protein-based glues was developed through rational design at the molecular level. These glues, assembled through supramolecular methods, exhibited robust liquid-liquid phase separation triggered by arginine. The encoded arginine moieties significantly enhanced the molecular interactions in the material, resulting in ultrastrong adhesion on various surfaces. These protein-based glues demonstrated quick hemostasis, outstanding tissue regeneration, good biocompatibility, and superior antibacterial capacity.

ADVANCED MATERIALS (2022)

Add to Collection

Article Multidisciplinary Sciences

Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage

Guangyu Bao et al.

Summary: Non-compressible hemorrhage is a challenge in trauma patients, but researchers have developed a new type of bioadhesive that can rapidly absorb fluids promoting blood clotting and demonstrate good adhesion and hemostatic effects in ex vivo and in vivo models.

NATURE COMMUNICATIONS (2022)

Add to Collection

Article Engineering, Biomedical

A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries

Guoqing Wang et al.

Summary: A new robust hemostatic bioadhesive has been developed, which can rapidly and strongly gel on wet tissues, achieving rapid hemostasis and promoting wound healing.

BIOMATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Proteinaceous Fibers with Outstanding Mechanical Properties Manipulated by Supramolecular Interactions

Jing Sun et al.

Summary: This study demonstrates a new type of engineered protein fibers using electrostatic complexation of cationic elastins and anionic surfactants, achieving significant alternation of fibers' mechanical properties through multiple supramolecular interactions. These fibers exhibit high plasticity, forming different structures and strong fluorescence under specific conditions. This study offers new strategies for the mechanical regulation of engineered protein fibers.

CCS CHEMISTRY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Promoting Oral Mucosal Wound Healing with a Hydrogel Adhesive Based on a Phototriggered S-Nitrosylation Coupling Reaction

Wenjie Zhang et al.

Summary: The wet and dynamic environment of the mouth poses challenges for local treatment of oral mucosal diseases, but a newly developed photo-crosslinking hydrogel adhesive shows promise in creating a favorable microenvironment for tissue repair and shortening healing time.

ADVANCED MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

An Artificial Phase-Transitional Underwater Bioglue with Robust and Switchable Adhesion Performance

Lingling Xiao et al.

Summary: By combining supramolecular assembly and rational protein design, a temperature-sensitive wet bioadhesive with actively tunable mechanical performance has been developed.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Engineered Protein Photo-Thermal Hydrogels for Outstanding In Situ Tongue Cancer Therapy

Juanjuan Su et al.

Summary: A new class of near-infrared light-responsive hydrogel with extraordinary photothermal therapy has been developed for in situ tongue tumors, showing good biocompatibility and efficient tumor eradication without side effects on surrounding normal tissues, providing great potential for clinical treatment of oral cancers as a non-surgical alternative.

ADVANCED MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Genetically Engineered Polypeptide Adhesive Coacervates for Surgical Applications

Jing Sun et al.

Summary: A new type of non-swelling protein adhesive has been developed for underwater and in vivo applications, utilizing electrostatic complexation between supercharged polypeptides and oppositely charged surfactants to form ultra-strong adhesive coacervates. Its adhesion capability surpasses commercial products and other protein-based adhesives in both ambient and underwater conditions, as demonstrated by ex vivo and in vivo experiments showing persistent adhesive performance and outstanding wound sealing and healing behaviors.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Biomimetic Glycopolypeptide Hydrogels with Tunable Adhesion and Microporous Structure for Fast Hemostasis and Highly Efficient Wound Healing

Lin Teng et al.

Summary: Two kinds of coordinated and covalent glycopolypeptide hydrogels with tunable tissue adhesion strength and microporous structure were fabricated. The microporous size mainly controls hemostasis, with hydrogels with larger pores achieving the fastest hemostasis and lowest blood loss. Overall, the glycopolypeptide hydrogels showed superior healing functions in animal models, with full wound closure and regeneration of dermis and epidermis with hair follicles.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Multidisciplinary Sciences

Ultra-strong bio-glue from genetically engineered polypeptides

Chao Ma et al.

Summary: The study introduces a biocompatible and biodegradable protein-based adhesive with high adhesion strength, suitable for hemostasis and wound healing applications, outperforming commercial products in terms of biomedical glue performance.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Multidisciplinary Sciences

Ultrafast, tough, and adhesive hydrogel based on hybrid photocrosslinking for articular cartilage repair in water-filled arthroscopy

Yujie Hua et al.

Summary: The study introduces a versatile hybrid photocrosslinkable hydrogel for tissue engineering applications in water-irrigated, arthroscopic cartilage repair. This hydrogel exhibits ultrafast gelation, high mechanical strength, and strong adhesion to native tissue, making it suitable for direct use in arthroscopic treatments.

SCIENCE ADVANCES (2021)

Add to Collection

Article Engineering, Biomedical

Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue

Hyunwoo Yuk et al.

Summary: This adhesive paste, inspired by barnacle glue, effectively seals tissues in less than 15 seconds regardless of blood coagulation rate. With a design based on adhesive proteins embedded in a lipid-rich matrix, the paste resorbs slowly over weeks and forms strong interfaces with blood-covered tissues, outperforming commercial haemostatic agents. It may be beneficial in treating severe bleeding, even in individuals with coagulopathies.

NATURE BIOMEDICAL ENGINEERING (2021)

Add to Collection

Article Chemistry, Multidisciplinary

A Novel Double-Crosslinking-Double-Network Design for Injectable Hydrogels with Enhanced Tissue Adhesion and Antibacterial Capability for Wound Treatment

Lei Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection

Article Nanoscience & Nanotechnology

Coadministration of an Adhesive Conductive Hydrogel Patch and an Injectable Hydrogel to Treat Myocardial Infarction

Tengling Wu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Add to Collection

Review Nanoscience & Nanotechnology

Overcoming the translational barriers of tissue adhesives

Gonzalo Munoz Taboada et al.

NATURE REVIEWS MATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Engineered Near-Infrared Fluorescent Protein Assemblies for Robust Bioimaging and Therapeutic Applications

Jingjing Li et al.

ADVANCED MATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Rapid Fabrication of Self-Healing, Conductive, and Injectable Gel as Dressings for Healing Wounds in Stretchable Parts of the Body

Sixiang Li et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Liquid Bandage Harvests Robust Adhesive, Hemostatic, and Antibacterial Performances as a First-Aid Tissue Adhesive

Yufei Ma et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Injectable and NIR-Responsive DNA-Inorganic Hybrid Hydrogels with Outstanding Photothermal Therapy

Bin Liu et al.

ADVANCED MATERIALS (2020)

Add to Collection

Review Engineering, Biomedical

Multifunctional Biomedical Adhesives

Rattapol Pinnaratip et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Hyaluronic Acid-Based Activatable Nanomaterials for Stimuli-Responsive Imaging and Therapeutics: Beyond CD44-Mediated Drug Delivery

Ki Young Choi et al.

ADVANCED MATERIALS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Paintable and Rapidly Bondable Conductive Hydrogels as Therapeutic Cardiac Patches

Shuang Liang et al.

ADVANCED MATERIALS (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Injectable Hydrogel with Slow Degradability Composed of Gelatin and Hyaluronic Acid Cross-Linked by Schiff's Base Formation

Takuro Hozumi et al.

BIOMACROMOLECULES (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding

DaShawn A. Hickman et al.

ADVANCED MATERIALS (2018)

Add to Collection

Article Multidisciplinary Sciences

Tough adhesives for diverse wet surfaces

J. Li et al.

SCIENCE (2017)

Add to Collection

Review Chemistry, Physical

Complex coacervates based on recombinant mussel adhesive proteins: their characterization and applications

Hyo Jeong Kim et al.

SOFT MATTER (2017)

Add to Collection

Review Biochemistry & Molecular Biology

Vascular wall extracellular matrix proteins and vascular diseases

Junyan Xu et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

Release of glutaraldehyde from an albumin-glutaraldehyde tissue adhesive causes significant in vitro and in vivo toxicity

W Fürst et al.

ANNALS OF THORACIC SURGERY (2005)

Add to Collection

Review Biotechnology & Applied Microbiology

Genetic toxicity and carcinogenicity studies of glutaraldehyde - a review

E Zeiger et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2005)

Add to Collection

Article Engineering, Biomedical

Cytotoxicity of glutaraldehyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosis

JE Gough et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH (2002)

Add to Collection

Article Engineering, Biomedical

Cytotoxicity, blood compatibility and antimicrobial activity of two cyanoacrylate glues for surgical use

L Montanaro et al.

BIOMATERIALS (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.