Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 138, Issue 23, Pages 7212-7215Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.6b00406
Keywords
-
Categories
Funding
- Singapore National Research Foundation
- GlaxoSmithKline
- Ministry of Education of Singapore
- Nanyang Technological University
- China's National Key program for Basic Research [2010CB 126105]
- Thousand Talent Plan
- NSF of China [21132003, 21472028]
- Guizhou Province Returned Oversea Student Science and Technology Activity Program
- Guizhou University
- Science and Technology Department of Guizhou Province
Ask authors/readers for more resources
Carbene-catalyzed reaction of carboxylic esters has the potential to offer effective synthetic solutions that cannot be readily achieved-by using the more conventional aldehyde-type substrates. Here we report the first carbene-catalyzed: dynamic kinetic resolution of alpha,alpha-disubstituted carboxylic esters with up to 99:1 er and 99% yield. The present study clearly illustrates the unique power of carbene-catalyzed reactions of readily available and easy to handle carboxylic esters:
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
