☆ 4.8 Article

Silica Nanoparticles Promote the Megakaryocyte Maturation and Differentiation: Potential Implications for Hematological Homeostasis

ACS APPLIED MATERIALS & INTERFACES (2023)

Related references

Note: Only part of the references are listed.

Article Medicine, Research & Experimental

PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis

Youliang Zhao et al.

Summary: This study demonstrates the potential value of immune checkpoint inhibitors, particularly PD-1/PD-L1 inhibitors, in the treatment of silica-induced pulmonary fibrosis. The findings suggest that these inhibitors can modulate immune system disruption caused by silica exposure and provide new ideas for the treatment of fibrosis-related diseases.

BIOMEDICINE & PHARMACOTHERAPY (2022)

Add to Collection

Article Environmental Sciences

Distribution and sources of PM2.5-bound free silica in the atmosphere of hyper-arid regions in Hotan, North-West China

Huibin Liu et al.

Summary: This study found that the concentration of silica dioxide (α-SiO2) in PM2.5 was higher during dust period and lower during non-dust period in urban areas. The atmospheric visibility during dust period was mainly influenced by the content of atmospheric floating dust. Additionally, the sources of α-SiO2 and PM2.5 were different during dust period and non-dust period.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Add to Collection

Review Pharmacology & Pharmacy

Indirect mediators of systemic health outcomes following nanoparticle inhalation exposure

Ekaterina Mostovenko et al.

Summary: The field of nanoscience has revealed the wide diversity of nano-scale particulates from natural and anthropogenic sources, raising concerns about their impacts on human health. Inhalation is the primary route of entry, depositing nanoparticles deep into the lungs and potentially affecting organs like the cardiovascular system and brain. Research has shown that the translocation of nanoparticles from the lungs to the circulation, as well as the release of molecules from the lungs into the bloodstream, can lead to various systemic outcomes.

PHARMACOLOGY & THERAPEUTICS (2022)

Add to Collection

Article Toxicology

The Foam Cell Formation Associated With Imbalanced Cholesterol Homeostasis Due to Airborne Magnetite Nanoparticles Exposure

Haiyi Yu et al.

Summary: Fine particulate matter (PM) is a major environmental factor contributing to the development of atherosclerosis. This study found that exposure to PM promoted the formation of foam cells, a crucial pathological process in atherosclerosis. Additionally, magnetite nanoparticles were identified as a key toxic component of PM in facilitating foam cell formation.

TOXICOLOGICAL SCIENCES (2022)

Add to Collection

Article Multidisciplinary Sciences

In vitro impact preliminary assessment of airborne particulate from metalworking and woodworking industries

Ilona Pavlovska et al.

Summary: In this study, various testing approaches were utilized to evaluate the effects of occupational pollutants on tissues, coupled with 3D airway epithelial tissues to mimic exposure conditions. Tissue viability was assessed using an MTT assay, gene expression levels were analyzed using RT-qPCR, and it was found that exposure to workplace pollutants had a slight impact on lung epithelial cell proliferation.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Environmental Sciences

Activation of Nrf2/HO-1 signaling pathway attenuates ROS-mediated autophagy induced by silica nanoparticles in H9c2 cells

Guanqun Cui et al.

Summary: This study found that SiNPs induce cardiovascular toxicity through oxidative stress-mediated autophagy, and the Nrf2/HO-1 pathway negatively regulates autophagy.

ENVIRONMENTAL TOXICOLOGY (2021)

Add to Collection

Article Toxicology

Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation

Xiaoting Jin et al.

Summary: The study found that exposure to PM promotes thrombopoiesis in a concentration-dependent manner, inducing maturation and development of megakaryocytes by causing morphological changes, DNA ploidy occurrence, and alterations in biomarkers for platelet formation. The proteomics assay revealed that the main metabolic pathway regulating these changes was mitochondrial oxidative phosphorylation (OXPHOS). The findings suggest a potential perturbation of haze exposure in thrombopoiesis from megakaryocytes, providing new insights for assessing health risks from PM pollution.

PARTICLE AND FIBRE TOXICOLOGY (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation

Yifan Wu et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Add to Collection

Article Immunology

Membrane budding is a major mechanism of in vivo platelet biogenesis

Kathryn S. Potts et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Add to Collection

Article Materials Science, Biomaterials

Controlled drug release from polyelectrolyte-drug conjugate nanoparticles

Ruginn Catarata et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Add to Collection

Article Dermatology

Support for the Safe Use of Zinc Oxide Nanoparticle Sunscreens: Lack of Skin Penetration or Cellular Toxicity after Repeated Application in Volunteers

Yousuf H. Mohammed et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)

Add to Collection

Article Nanoscience & Nanotechnology

Porous Se@SiO2 nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model

Chunlin Li et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Add to Collection

Editorial Material Critical Care Medicine

The world is failing on silicosis

[Anonymous]

LANCET RESPIRATORY MEDICINE (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Age-Dependent Translocation of Gold Nanoparticles across the Air-Blood Barrier

Akira Tsuda et al.

ACS NANO (2019)

Add to Collection

Article Pharmacology & Pharmacy

Silica Nanoparticle-induced Cytokine Responses in BEAS-2B and HBEC3-KT Cells: Significance of Particle Size and Signalling Pathways in Different Lung Cell Cultures

Marit Lag et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2018)

Add to Collection

Article Environmental Sciences

Risk assessment of silica nanoparticles on liver injury in metabolic syndrome mice induced by fructose

Jianmei Li et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Graphene Oxide-Silver Nanoparticles Nanocomposite Stimulates Differentiation in Human Neuroblastoma Cancer Cells (SH-SY5Y)

Sangiliyandi Gurunathan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Add to Collection

Review Materials Science, Biomaterials

Personalized protein corona on nanoparticles and its clinical implications

Claudia Corbo et al.

BIOMATERIALS SCIENCE (2017)

Add to Collection

Review Oncology

Normal platelet function

Michael Holinstat

CANCER AND METASTASIS REVIEWS (2017)

Add to Collection

Review Cardiac & Cardiovascular Systems

Platelets and cardiovascular risk

Barbara Renga et al.

ACTA CARDIOLOGICA (2017)

Add to Collection

Article Engineering, Biomedical

The stimulatory effect of silica nanoparticles on osteogenic differentiation of human mesenchymal stem cells

Xing Yang et al.

BIOMEDICAL MATERIALS (2017)

Add to Collection

Article Materials Science, Biomaterials

In vivo behaviors of Ca(OH)2 activated nano SiO2 (nCa/nSi=3) cement in rabbit model

Qing Lin et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

Add to Collection

Article Oncology

The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line

Hai-tao Wang et al.

CANCER MEDICINE (2016)

Add to Collection

Article Engineering, Environmental

Effects of SiO2 nanoparticles on phospholipid membrane integrity and fluidity

Xiaoran Wei et al.

JOURNAL OF HAZARDOUS MATERIALS (2015)

Add to Collection

Article Medicine, General & Internal

Venous thrombosis

Alisa S. Wolberg et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Add to Collection

Article Nanoscience & Nanotechnology

Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation

Abderrahim Nemmar et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

Cardiovascular Toxicity of Different Sizes Amorphous Silica Nanoparticles in Rats After Intratracheal Instillation

Zhongjun Du et al.

CARDIOVASCULAR TOXICOLOGY (2013)

Add to Collection

Review Cell Biology

The incredible journey: From megakaryocyte development to platelet formation

Kellie R. Machlus et al.

JOURNAL OF CELL BIOLOGY (2013)

Add to Collection

Article Multidisciplinary Sciences

Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

Yang Yu et al.

PLOS ONE (2013)

Add to Collection

Article Nanoscience & Nanotechnology

Amorphous silica nanoparticles aggregate human platelets: potential implications for vascular homeostasis

J. Jose Corbalan et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)

Add to Collection

Article Chemistry, Multidisciplinary

Chemistry of Aqueous Silica Nanoparticle Surfaces and the Mechanism of Selective Peptide Adsorption

Siddharth V. Patwardhan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Add to Collection

Article Medicine, General & Internal

Silicosis

Chi Chiu Leung et al.

LANCET (2012)

Add to Collection

Article Engineering, Biomedical

The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles

Kee Woei Ng et al.

BIOMATERIALS (2011)

Add to Collection

Review Hematology

Transcription factor networks in erythroid cell and megakaryocyte development

Louis C. Dore et al.

BLOOD (2011)

Add to Collection

Article Hematology

c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation

P. Garcia et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)

Add to Collection

Article Pharmacology & Pharmacy

Histological analysis of 70-nm silica particles-induced chronic toxicity in mice

Hikaru Nishimori et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2009)

Add to Collection

Article Chemistry, Multidisciplinary

Size-Dependent Cytotoxicity of Monodisperse Silica Nanoparticles in Human Endothelial Cells

Dorota Napierska et al.

SMALL (2009)

Add to Collection

Article Chemistry, Multidisciplinary

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

Tian Xia et al.

ACS NANO (2008)

Add to Collection

Article Hematology

From hematopoietic stem cells to platelets

Y. Chang et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)

Add to Collection

Review Biochemistry & Molecular Biology

Molecular mechanisms of megakaryopoiesis

G. Szalai et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2006)

Add to Collection

Article Critical Care Medicine

The inflammatory role of platelets in cystic fibrosis

BP O'Sullivan et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Add to Collection

Article Hematology

Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development

AG Muntean et al.

BLOOD (2005)

Add to Collection

Review Environmental Sciences

Nanotoxicology:: An emerging discipline evolving from studies of ultrafine particles

G Oberdörster et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2005)

Add to Collection

© Peeref 2019-2024. All rights reserved.