SERS Nanowire Chip and Machine Learning-Enabled Classification of Wild-Type and Antibiotic-Resistant Bacteria at Species and Strain Levels

Article Biochemical Research Methods

Detection of multi-resistant clinical strains of E. coli with Raman spectroscopy

Amir Nakar et al.

Summary: This study used Raman spectroscopy to differentiate between resistant and sensitive strains of Escherichia coli, which can help in the rapid and accurate identification of antibiotic-resistant bacteria.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

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Review Microbiology

Infectious disease in an era of global change

Rachel E. Baker et al.

Summary: Global changes such as climate change, urbanization, and global travel and trade have impacted the emergence and spread of infectious diseases. Recent decades have seen a wave of severe infectious disease outbreaks, including COVID-19 and Zika virus disease, which have had devastating effects worldwide.

NATURE REVIEWS MICROBIOLOGY (2022)

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Article Materials Science, Multidisciplinary

Mesoporous Ag-TiO2 based nanocage like structure as sensitive and recyclable low-cost SERS substrate for biosensing applications

Sathi Das et al.

Summary: A porous Ag-TiO2 film with a nanocage-like structure was fabricated as a sensitive, recyclable, and low-cost SERS substrate using facile methods. The substrate demonstrated high sensitivity and accuracy in catalyzing dye degradation and detecting urea.

OPTICAL MATERIALS (2022)

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Article Infectious Diseases

Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution

Ruggero La Rosa et al.

Summary: Antibiotic resistance is predicted to be the biggest threat to human health by 2050, but we often overlook the difficulty in diagnosing and treating many bacterial infections. Persistent infections caused by opportunistic bacteria are becoming more successful in immunocompromised patients, even when the bacteria are susceptible to antibiotics. The mechanisms of persistence are complex and challenging to diagnose and treat.

ANTIBIOTICS-BASEL (2022)

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Article Nanoscience & Nanotechnology

Highly ordered arrays of hat-shaped hierarchical nanostructures with different curvatures for sensitive SERS and plasmon-driven catalysis

Chao Zhang et al.

Summary: Regulation of hot spots using hat-shaped hierarchical nanostructures shows promising potential in various applications, including SERS and plasmon-driven catalysis. The constructed platform, with narrow gaps produced by MoS2 films and curvature of space, exhibits superior SERS capability and achieves ultrasensitive detection, as well as real-time monitoring of catalytic conversion.

NANOPHOTONICS (2022)

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Article Materials Science, Multidisciplinary

A highly sensitive SERS substrate based on a mesoporous Ag-TiO2 thin film for the detection of dye molecules

Sathi Das et al.

Summary: This study presents a technique for fast, accurate, and molecular-specific detection of dyes at ultra-trace levels using surface-enhanced Raman spectroscopy (SERS). The researchers explored a highly sensitive Ag-TiO2 thin film with a nanocage structure for SERS applications. The fabricated SERS substrate effectively detected different dyes at low concentrations, demonstrating its potential for practical applications.

MATERIALS ADVANCES (2022)

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Article Chemistry, Physical

Ultra-sensitive and fast optical detection of the spike protein of the SARS-CoV-2 using AgNPs/SiNWs nanohybrid based sensors

Kais Daoudi et al.

Summary: The study focused on developing a SERS sensor to detect the SARS-CoV-2 spike protein, using silicon nanowires (SiNWs) substrate and plasmonic silver nanoparticles (AgNPs) decoration to enhance sensing. The results indicated promising potential for SERS as an innovative tool in early infection diagnosis.

SURFACES AND INTERFACES (2021)

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Review Chemistry, Multidisciplinary

Silicon Nanowires Synthesis by Metal-Assisted Chemical Etching: A Review

Antonio Alessio Leonardi et al.

Summary: This article discusses the emerging technology of metal-assisted chemical etching (MACE) for the fabrication of silicon nanowires, comparing all the main routes for Si NWs and analyzing factors such as equipment cost, process complexity, repeatability, and the potential for commercial transfer in the field of microelectronics.

NANOMATERIALS (2021)

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Article Microbiology

Hybrid Assembly Provides Improved Resolution of Plasmids, Antimicrobial Resistance Genes, and Virulence Factors in Escherichia coli and Klebsiella pneumoniae Clinical Isolates

Abdolrahman Khezri et al.

Summary: This study utilized different sequencing platforms to sequence bacteria from clinical samples and tested multiple genome assembly methods. The results indicated that hybrid assembly performed better in predicting factors related to microbial pathogenicity.

MICROORGANISMS (2021)

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Article Materials Science, Multidisciplinary

Investigation of silver decorated silicon nanowires as ultrasensitive and cost-effective surface-enhanced Raman substrate

Laser Assisted et al.

Summary: The fabrication of silicon nanowires by metal-assisted chemical etching and deposition of silver nanoparticles by the electroless method can be used for SERS detection of organic pollutants. Study shows that increasing the length of SiNWs decreases the enhancement of SERS, and SERS has potential in discriminating mixed dyes.

THIN SOLID FILMS (2021)

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Article Nanoscience & Nanotechnology

Fabrication of low cost highly structured silver capped aluminium nanorods as SERS substrate for the detection of biological pathogens

Sathi Das et al.

Summary: Low cost highly structured silver capped aluminium nanorods were fabricated as a surface enhanced Raman spectroscopy substrate using glancing angle deposition, achieving Raman signal detection for Rhodamine 6G down to 10(-15) molar concentration. The developed SERS substrate successfully recorded Raman spectra for Escherichia coli bacteria with varying concentrations, demonstrating significant signal enhancement compared to uncapped silver nanorods.

NANOTECHNOLOGY (2021)

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Review Microbiology

Applications of Raman Spectroscopy in Bacterial Infections: Principles, Advantages, and Shortcomings

Liang Wang et al.

Summary: The rapid identification of bacterial pathogens and profiling of antibiotic resistance are crucial for precise treatment of infectious diseases. Various accurate, reliable, and time-efficient conventional and molecular methods have been developed for in vitro diagnostics.

FRONTIERS IN MICROBIOLOGY (2021)

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Article Food Science & Technology

Burden of foodborne diseases: think global, act local

Sara M. Pires et al.

Summary: National burden of foodborne disease studies are crucial for establishing food safety as a public health priority, ranking diseases, and informing interventions. Despite progress in implementing these studies, the current landscape of disease burden remains disjointed, making it challenging for researchers to translate findings into policy recommendations.

CURRENT OPINION IN FOOD SCIENCE (2021)

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Article Biochemical Research Methods