Journal
CELL REPORTS MEDICINE
Volume 4, Issue 1, Pages 1-2Publisher
CELL PRESS
DOI: 10.1016/j.xcrm.2022.100903
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The study reveals that autoantibodies in systemic lupus erythematosus (SLE) can have a protective role by neutralizing type I interferons (IFNs) and restraining the activation of pathogenic B cells.
B cells and autoantibodies have well-described pathological roles in systemic lupus erythematosus (SLE). Bradford et al.(1) now provide evidence that autoantibodies can also be protective by neutralizing type I interferons (IFNs) and restraining the activation of pathogenic B cells.
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