4.2 Article

Smart plasmonic hydrogels based on gold and silver nanoparticles for biosensing application

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ELSEVIER
DOI: 10.1016/j.cobme.2022.100413

Keywords

Smart materials; Plasmonic hydrogel; Biosensing

Funding

  1. Foundation for Polish Science (FNP) [POIR.04.04.00-00-5ED7/18-00]
  2. European Union under the European Regional Development Fund
  3. National Agency for Academic Exchange (NAWA) [PPI/APM/2018/1/00045/U/001]
  4. Polish Ministry of Science and Higher Education through scholarships for outstanding young scientists

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The fast, accurate, and reusable detection track is becoming increasingly important in the field of biosensing. Optical biosensing using plasmonic nanoparticles and hydrogels can enhance sensing precision and detection limit.
The importance of having a fast, accurate, and reusable track for detection has led to an increase investigation in the field of biosensing. Optical biosensing using plasmonic nanoparticles, such as gold and silver, introduces localized surface plasmon resonance (LSPR) sensors. LSPR biosensors are progressive in their sensing precision and detection limit. Also, the possi-bility to tune the sensing range by varying the size and shape of the particles has made them extremely useful. Hydrogels being hydrophilic 3D networks can be beneficial when used as matrices, because of a more efficient biorecognition. Stimuli-responsive hydrogels can be great candidates, as their response to a stimulus can increase recognition and detection. This article highlights recent advances in combining hydrogels as a matrix and plasmonic nanoparticles as sensing elements. The end capability and diversity of these novel biosensors in different applications in the near future are discussed.

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