Journal
JOURNAL OF IMAGING
Volume 8, Issue 10, Pages -Publisher
MDPI
DOI: 10.3390/jimaging8100292
Keywords
linear tomosynthesis; geometric calibration; histologic imaging; calcium scoring
Categories
Funding
- Division of Intramural Research, National Heart, Lung and Blood Institute, Intramural Research Program, National Institutes of Health, USA [HL006142-05]
Ask authors/readers for more resources
This paper presents a method for online calibration in a linear tomosynthesis scanner. By attaching a layer of randomly dispersed micro glass beads or calcium particles to the bottom of the sample stage, the trajectory of the scanning stage can be determined for each scan, avoiding blurring and artifacts in the images caused by errors in geometric information.
In a linear tomosynthesis scanner designed for imaging histologic samples of several centimeters size at 10 mu m resolution, the mechanical instability of the scanning stage (+/- 10 mu m) exceeded the resolution of the image system, making it necessary to determine the trajectory of the stage for each scan to avoid blurring and artifacts in the images that would arise from the errors in the geometric information used in 3D reconstruction. We present a method for online calibration by attaching a layer of randomly dispersed micro glass beads or calcium particles to the bottom of the sample stage. The method was based on a parametric representation of the rigid body motion of the sample stage-marker layer assembly. The marker layer was easy to produce and proven effective in the calibration procedure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available