4.3 Article

Deep Learning Model for Computer-Aided Diagnosis of Urolithiasis Detection from Kidney-Ureter-Bladder Images

Journal

BIOENGINEERING-BASEL
Volume 9, Issue 12, Pages -

Publisher

MDPI
DOI: 10.3390/bioengineering9120811

Keywords

computer-aided diagnosis; kidney-ureter-bladder; kidney stone; deep learning; residual network

Funding

  1. Ministry of Science and Technology, Taiwan, R.O.C.
  2. [MOST 110-2222-E-992-006-]

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This study proposes a CAD system for KUB imaging based on a deep learning model to assist emergency room clinicians in accurately diagnosing urolithiasis. By collecting a dataset of KUB images, the model was trained and tested, demonstrating good performance in detecting urolithiasis. The results of this research are expected to help clinicians diagnose urolithiasis accurately and reduce unnecessary radiation exposure and medical costs.
Kidney-ureter-bladder (KUB) imaging is a radiological examination with a low cost, low radiation, and convenience. Although emergency room clinicians can arrange KUB images easily as a first-line examination for patients with suspicious urolithiasis, interpreting the KUB images correctly is difficult for inexperienced clinicians. Obtaining a formal radiology report immediately after a KUB imaging examination can also be challenging. Recently, artificial-intelligence-based computer-aided diagnosis (CAD) systems have been developed to help clinicians who are not experts make correct diagnoses for further treatment more effectively. Therefore, in this study, we proposed a CAD system for KUB imaging based on a deep learning model designed to help first-line emergency room clinicians diagnose urolithiasis accurately. A total of 355 KUB images were retrospectively collected from 104 patients who were diagnosed with urolithiasis at Kaohsiung Chang Gung Memorial Hospital. Then, we trained a deep learning model with a ResNet architecture to classify KUB images in terms of the presence or absence of kidney stones with this dataset of pre-processed images. Finally, we tuned the parameters and tested the model experimentally. The results show that the accuracy, sensitivity, specificity, and F1-measure of the model were 0.977, 0.953, 1, and 0.976 on the validation set and 0.982, 0.964, 1, and 0.982 on the testing set, respectively. Moreover, the results demonstrate that the proposed model performed well compared to the existing CNN-based methods and was able to detect urolithiasis in KUB images successfully. We expect the proposed approach to help emergency room clinicians make accurate diagnoses and reduce unnecessary radiation exposure from computed tomography (CT) scans, along with the associated medical costs.

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