Journal
ADVANCED MATERIALS
Volume 27, Issue 44, Pages 7043-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201503323
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Funding
- NC TraCS, NIH's Clinical and Translational Science Awards (CTSA, NIH) at UNC-CH [1UL1TR001111]
- State of North Carolina
- National Science Foundation (NSF)
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A core-shell nanovehicle coated with a platelet membrane (PM) is developed for targeted and site-specific delivery of an extracellularly active drug and an intracellular functional small-molecular drug, leading to enhanced antitumor efficacy. This PM-coated nanovehicle can also effectively eliminate the circulating tumor cells in vivo and inhibit development of tumor metastasis.
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