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Human mini-blood-brain barrier models for biomedical neuroscience research: a review

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Extracellular matrix-based materials for regenerative medicine

George S. Hussey et al.

NATURE REVIEWS MATERIALS (2018)

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In-vitro blood-brain barrier modeling: A review of modern and fast-advancing technologies

Farzane Sivandzade et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2018)

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Matrigel uses in cell biology and for the identification of thymosin 4, a mediator of tissue regeneration

Hynda K. Kleinman et al.

APPLIED BIOLOGICAL CHEMISTRY (2018)

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Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics

Sonja Bergmann et al.

NATURE PROTOCOLS (2018)

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Coaxial Cell Printing of Freestanding, Perfusable, and Functional In Vitro Vascular Models for Recapitulation of Native Vascular Endothelium Pathophysiology

Ge Gao et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Benchmarking in vitro tissue-engineered blood-brain barrier models

Jackson G. DeStefano et al.

FLUIDS AND BARRIERS OF THE CNS (2018)

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Bioprinting of artificial blood vessels

Hooi Yee Ng et al.

INTERNATIONAL JOURNAL OF BIOPRINTING (2018)

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Article Clinical Neurology

Glucose Transporter Type 1 Deficiency Syndrome: Developmental Delay and Early-Onset Ataxia in a Novel Mutation of the SLC2A1 Gene

Tullio Messana et al.

JOURNAL OF PEDIATRIC NEUROSCIENCES (2018)

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A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport

Nienke R. Wevers et al.

FLUIDS AND BARRIERS OF THE CNS (2018)

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Modeling the blood-brain barrier: Beyond the endothelial cells

Benjamin D. Gastfriend et al.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2018)

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Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation

Moriah E. Katt et al.

FLUIDS AND BARRIERS OF THE CNS (2018)

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Community-acquired bacterial meningitis

Joost M. Costerus et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2017)

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The Translational Significance of the Neurovascular Unit*

Heather L. McConnell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

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Induced pluripotent stem cell technology: a decade of progress

Yanhong Shi et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

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Animal experimentation: A look into ethics, welfare and alternative methods

Marcos Rassi Fernandes et al.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA (2017)

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Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

Choi-Fong Cho et al.

NATURE COMMUNICATIONS (2017)

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Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control

Roberta Haddad-Tovolli et al.

FRONTIERS IN NEUROSCIENCE (2017)

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Engineering the human blood-brain barrier in vitro

John J. Jamieson et al.

JOURNAL OF BIOLOGICAL ENGINEERING (2017)

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Ultrathin Porated Elastic Hydrogels As a Biomimetic Basement Membrane for Dual Cell Culture

Amanda S. Pellowe et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2017)

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Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells

Antje Appelt-Menzel et al.

STEM CELL REPORTS (2017)

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Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson's disease?

Junichi Matsumoto et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)

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Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier

Xiaohe Tian et al.

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A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes

Seokyoung Bang et al.

SCIENTIFIC REPORTS (2017)

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Integration of neurogenesis and angiogenesis models for constructing a neurovascular tissue

Hiroyuki Uwamori et al.

SCIENTIFIC REPORTS (2017)

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Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment

Guoyou Huang et al.

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Tissue Engineered Bio-Blood-Vessels Constructed Using a Tissue-Specific Bioink and 3D Coaxial Cell Printing Technique: A Novel Therapy for Ischemic Disease

Ge Gao et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

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Correction Biochemistry & Molecular Biology

Endothelial basement membrane laminin 511 is essential for shear stress response (vol 36, pg 183, 2017)

Jacopo Di Russo et al.

EMBO JOURNAL (2017)

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The Central Nervous System and the Gut Microbiome

Gil Sharon et al.

CELL (2016)

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Pathophysiological implications of neurovascular P450 in brain disorders

Chaitali Ghosh et al.

DRUG DISCOVERY TODAY (2016)

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In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

Hans C. Helms et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)

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A practical guide to hydrogels for cell culture

Steven R. Caliari et al.

NATURE METHODS (2016)

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Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks

Jeroen Rouwkema et al.

TRENDS IN BIOTECHNOLOGY (2016)

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3D microtumors in vitro supported by perfused vascular networks

Agua Sobrino et al.

SCIENTIFIC REPORTS (2016)

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Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips

Kimberly A. Homan et al.

SCIENTIFIC REPORTS (2016)

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A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors

Hui Xu et al.

SCIENTIFIC REPORTS (2016)

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Assessment of Blood-Brain Barrier Disruption in Stroke

Andrea Kassner et al.

STROKE (2015)

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The Blood-Brain Barrier

Richard Daneman et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)

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Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

Hansang Cho et al.

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Engineering an in vitro air-blood barrier by 3D bioprinting

Lenke Horvath et al.

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Creating perfused functional vascular channels using 3D bio-printing technology

Vivian K. Lee et al.

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Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

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ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

Young Hee Choi et al.

CURRENT PHARMACEUTICAL DESIGN (2014)

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Disruption of the blood-brain barrier in parkinson's disease: curse or route to a cure?

Heyne Lee et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2014)

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Differences in amyloid-β clearance across mouse and human blood-brain barrier models: Kinetic analysis and mechanistic modeling

Hisham Qosa et al.

NEUROPHARMACOLOGY (2014)

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Cell-Culture Models of the Blood-Brain Barrier

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STROKE (2014)

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Development, maintenance and disruption of the blood-brain barrier

Birgit Obermeier et al.

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Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain

Geeta Ramesh et al.

MEDIATORS OF INFLAMMATION (2013)

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Direct Plotting of Three-Dimensional Hollow Fiber Scaffolds Based on Concentrated Alginate Pastes for Tissue Engineering

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Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies

Daniela E. Eigenmann et al.

FLUIDS AND BARRIERS OF THE CNS (2013)

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Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems

Arati Sharma et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2012)

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Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Ethan S. Lippmann et al.

NATURE BIOTECHNOLOGY (2012)

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Engineering ECM signals into biomaterials

Ryan J. Wade et al.

MATERIALS TODAY (2012)

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The role of shear stress in Blood-Brain Barrier endothelial physiology

Luca Cucullo et al.

BMC NEUROSCIENCE (2011)

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Extracellular Matrix and Matrix Receptors in Blood-Brain Barrier Formation and Stroke

Kim M. Baeten et al.

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Bidirectional control of arteriole diameter by astrocytes

Grant R. J. Gordon et al.

EXPERIMENTAL PHYSIOLOGY (2011)

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β1-Integrin/matrix interactions support blood-brain barrier integrity

Britta Engelhardt

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)

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Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

Kathryn Hatherell et al.

JOURNAL OF NEUROSCIENCE METHODS (2011)

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez-Erviti et al.

NATURE BIOTECHNOLOGY (2011)

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Decellularized Porcine Brain Matrix for Cell Culture and Tissue Engineering Scaffolds

Jessica A. DeQuach et al.

TISSUE ENGINEERING PART A (2011)

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Extracellular Matrix Degradation and Remodeling in Development and Disease

Pengfei Lu et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

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Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

Yong Soon Chun et al.

ANATOMY & CELL BIOLOGY (2011)

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Recessive Mutations in the Gene Encoding the Tight Junction Protein Occludin Cause Band-like Calcification with Simplified Gyration and Polymicrogyria

Mary C. O'Driscoll et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2010)

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Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

Junmin Zhu

BIOMATERIALS (2010)

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Mechanisms Underlying Inflammation in Neurodegeneration

Christopher K. Glass et al.

CELL (2010)

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Identification and expression profiling of blood-brain barrier membrane proteins

Nitin Agarwal et al.

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Pericytes are required for blood-brain barrier integrity during embryogenesis

Richard Daneman et al.

NATURE (2010)

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Do astrocytes really exocytose neurotransmitters?

Nicola B. Hamilton et al.

NATURE REVIEWS NEUROSCIENCE (2010)

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Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture

Mark W. Tibbitt et al.

BIOTECHNOLOGY AND BIOENGINEERING (2009)

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Clearance of Amyloid-beta Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimer's Disease

R. Deane et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)

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Biophysical Interactions with Model Lipid Membranes: Applications in Drug Discovery and Drug Delivery

Chiranjeevi Peetla et al.

MOLECULAR PHARMACEUTICS (2009)

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Transvascular delivery of small interfering RNA to the central nervous system

Priti Kumar et al.

NATURE (2007)

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Blood-brain barrier transport of therapeutics via receptor-mediation

Angela R. Jones et al.

PHARMACEUTICAL RESEARCH (2007)

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Bidirectional control of CNS capillary diameter by pericytes

Claire M. Peppiatt et al.

NATURE (2006)

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Endothelial focal adhesions and barrier function

MH Wu

JOURNAL OF PHYSIOLOGY-LONDON (2005)

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Blood-brain barrier-specific properties of a human adult brain endothelial cell line

BB Weksler et al.

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