Journal
ADVANCED MATERIALS
Volume 27, Issue 33, Pages 4931-4937Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201501972
Keywords
aggregation-induced emission; antibiotics screening; bacterial imaging; bacterial susceptibility; high-throughput
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Funding
- National Basic Research Program of China (973 Program) [2013CB834701]
- University Grants Committee of Hong Kong [AoE/P-03/08]
- Research Grants Council of Hong Kong [604913, 16301614, N_HKUST604/14]
- Innovation and Technology Commission [ITCPD/17-9]
- Science and Technology Plan of Shenzhen [JCYJ20140425170011516]
- Science Fund of Guangdong Province [2014A030313659]
- Guangdong Innovative Research Team Program [201101C0105067115]
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A luminogen with aggregation-induced emission characteristics is reported for bacterial imaging and antibiotics screening studies. The luminogen can light up bacteria in a wash-free manner, which simplifies the imaging process and increases its accuracy in bacterial detection. It can also be applied to high-throughput screening of antibiotics and fast evaluation of bacterial susceptibility, giving reliable results in less than 5 h.
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