A Sneak peek (1970-2021) Into Phytochemistry and Ethnomedical Properties of Solanum Nigrum Linn (Makoi)

Introduction: Plants have always played a substantial role in the traditional medicine system worldwide. In India and other parts of the world, Solanum Nigrum Linn. is one of the most promising and reliable sources of medicine in the traditional medicine system. It is well known for its dynamic therapeutic properties. The concrete objective of selecting this plant is to consolidate its bioactive elements and possibly medicinal qualities. So that future scientists and researchers may progress novel pharmaceuticals for pre-clinical and clinical trials, which could be launched as new targeted therapeutic options.Method: This review summarized the previous three decades' worth of scientific publications from online databases such as Google Scholar, PubMed, ScienceDirect, Web of Science, and library books to assemble their possible phytopharmacological and therapeutic potentials.Results: From the ongoing research database, S. Nigrum possesses a plethora of active phytoconstituents like glycoproteins, polysaccharides, polyphenolic compounds, and glycoalkaloids which are responsible for various pharmacological activities such as antioxidant, anticancer, antitumor, hepatoprotective, antidiabetic, and anti-asthmatic etc.Conclusion: This mystic herb has exhibited numerous ethnomedical properties in humans. Our research findings provide clear evidence that S. Nigrum could be a potential natural source of several ailments and might be marketed as an alternative to contemporary medicines. The stem, flower, root, and seed contain numerous dynamic bioactive constituents that are unexplored. Future researchers have an excellent opportunity to investigate them and elucidate their biomedical scientific activities and mechanisms in different diseases.

Automated summary

Solanum Nigrum has been widely used in traditional medicine systems for its therapeutic properties. It contains various bioactive constituents that have potential pharmacological activities, including antioxidant, anticancer, antidiabetic, and anti-asthmatic effects. This plant could be a promising natural source for developing alternative medicines.