Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 72, Issue 9, Pages 1663-1677Publisher
SPRINGER BASEL AG
DOI: 10.1007/s00018-014-1819-5
Keywords
Satellite cells; Quiescent stem cells; Epigenetics; Non-coding RNA; DNA methylation; Growth factors
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Funding
- Ministry of Science and Technology of China [2014CB964700]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDA01010204]
- National Natural Science Foundation of China [31171420]
- One Hundred Talents Program of Chinese Academy of Sciences [2012OHTP02]
- Science and Technology Commission of Shanghai Municipality [12PJ1409700, 13JC1406500]
- CAS-CSIRO [GJHZ1504]
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Muscle stem cell (satellite cell) activation post muscle injury is a transient and critical step in muscle regeneration. It is regulated by physiological cues, signaling molecules, and epigenetic regulatory factors. The mechanisms that coherently turn on the complex activation process shortly after trauma are just beginning to be illuminated. In this review, we will discuss the current knowledge of satellite cell activation regulation.
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