Related references
Note: Only part of the references are listed.Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition
Sara Badodi et al.
CELL CYCLE (2015)
The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle
Indra A. Shaltiel et al.
JOURNAL OF CELL SCIENCE (2015)
Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression
Ho-Chang Jeong et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells
Inge The et al.
NATURE COMMUNICATIONS (2015)
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function
Job de Lange et al.
NATURE COMMUNICATIONS (2015)
APC/CCdh1 controls CtIP stability during the cell cycle and in response to DNA damage
Lorenzo Lafranchi et al.
EMBO JOURNAL (2014)
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C
Katharine L. Sackton et al.
NATURE (2014)
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
Masayuki Yamada et al.
GENES & DEVELOPMENT (2013)
The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors
Manuel Eguren et al.
NATURE COMMUNICATIONS (2013)
APC/C-Cdh1 coordinates neurogenesis and cortical size during development
Maria Delgado-Esteban et al.
NATURE COMMUNICATIONS (2013)
Degradation of Human RAP80 is Cell Cycle Regulated by Cdc20 and Cdh1 Ubiquitin Ligases
Hyun Jung Cho et al.
MOLECULAR CANCER RESEARCH (2012)
DNA Damage Signaling Triggers Degradation of Histone Methyltransferases through APC/CCdh1 in Senescent Cells
Akiko Takahashi et al.
MOLECULAR CELL (2012)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Lou K. Povlsen et al.
NATURE CELL BIOLOGY (2012)
Identification of Anaphase Promoting Complex Substrates in S-cerevisiae
Denis Ostapenko et al.
PLOS ONE (2012)
SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity
Hyun-Seok Kim et al.
CANCER CELL (2011)
Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner
Min Sup Song et al.
CELL (2011)
APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage
Xiomaris M. Cotto-Rios et al.
JOURNAL OF CELL BIOLOGY (2011)
Regulation of Ubiquitin Chain Initiation to Control the Timing of Substrate Degradation
Adam Williamson et al.
MOLECULAR CELL (2011)
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate
Michael J. Emanuele et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael R. Lieber
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Wip1 Directly Dephosphorylates Y-H2AX and Attenuates the DNA Damage Response
Hyukjin Cha et al.
CANCER RESEARCH (2010)
Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy
Teresa Davoli et al.
CELL (2010)
Cell cycle re-entry mechanisms after DNA damage checkpoints Giving it some gas to shut off the breaks!
Marcel A. T. M. van Vugt et al.
CELL CYCLE (2010)
Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2
F. Bassermann et al.
CELL DEATH AND DIFFERENTIATION (2010)
Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress
Liyong Zhang et al.
EMBO JOURNAL (2010)
Wild-type p53-induced Phosphatase 1 Dephosphorylates Histone Variant γ-H2AX and Suppresses DNA Double Strand Break Repair
Sung-Hwan Moon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair
Annamaria Mocciaro et al.
JOURNAL OF CELL BIOLOGY (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition
L. Macurek et al.
ONCOGENE (2010)
p53-and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress
L. Wiebusch et al.
ONCOGENE (2010)
Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression
Arne Lindqvist et al.
EMBO JOURNAL (2009)
Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis
Reinhard Sigl et al.
JOURNAL OF CELL SCIENCE (2009)
Cdc14B and APC/C tackle DNA damage
Peter De Wulf et al.
CELL (2008)
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
Florian Bassermann et al.
CELL (2008)
FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner
Jamila Laoukili et al.
CELL CYCLE (2008)
The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells
Eli Berdougo et al.
CELL CYCLE (2008)
Anaphase-promoting complex/cyclosome-Cdh1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase
Hyun Jung Park et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The anaphase-promoting complex/cyclosome controls repair and recombination by ubiquitylating Rhp54 in fission yeast
Michelle Trickey et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
Irene Garcia-Higuera et al.
NATURE CELL BIOLOGY (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The ubiquitin ligase APCCdh1 is required to maintain genome integrity in primary human cells
D. Engelbert et al.
ONCOGENE (2008)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
Bin Wang et al.
SCIENCE (2007)
Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C
Barbara Di Fiore et al.
JOURNAL OF CELL BIOLOGY (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
Julie J. Miller et al.
GENES & DEVELOPMENT (2006)
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
Dong Zhang et al.
CELL (2006)
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress
Xin Wang et al.
MOLECULAR CELL (2006)
Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry
MC Hall et al.
CELL CYCLE (2004)
Homologous recombination-mediated double-strand break repair
C Wyman et al.
DNA REPAIR (2004)
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
Y Moshe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts
F Baus et al.
EMBO JOURNAL (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Prophase destruction of Emi1 by the SCFβTrCP/Slimb ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase
F Margottin-Goguet et al.
DEVELOPMENTAL CELL (2003)
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A
CS Sorensen et al.
CANCER CELL (2003)
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
C Lukas et al.
NATURE CELL BIOLOGY (2003)
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1
JY Hsu et al.
NATURE CELL BIOLOGY (2002)
Separase, polo kinase, the kinetochore protein Slk19 and Spo12 function in a network that controls Cdc14 localization during early anaphase
F Stegmeier et al.
CELL (2002)
Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells
T Sudo et al.
EMBO JOURNAL (2001)
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses
SD Bao et al.
NATURE (2001)
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
JDR Reimann et al.
CELL (2001)
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
R Maya et al.
GENES & DEVELOPMENT (2001)
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
ZJ Guo et al.
GENES & DEVELOPMENT (2000)
Rapid destruction of human Cdc25A in response to DNA damage
N Mailand et al.
SCIENCE (2000)
Mitotic regulation of the APC activator proteins CDC20 and CDH1
ER Kramer et al.
MOLECULAR BIOLOGY OF THE CELL (2000)