Related references
Note: Only part of the references are listed.Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates
Zhen Wang et al.
AGING CELL (2014)
Spontaneous cyclization of polypeptides with a penultimate Asp, Asn or isoAsp at the N-terminus and implications for cleavage by aminopeptidase
Brian Lyons et al.
FEBS JOURNAL (2014)
One size does not fit all: The oligomeric states of αB crystallin
Scott P. Delbecq et al.
FEBS LETTERS (2013)
Pseudophosphorylated αB-Crystallin Is a Nuclear Chaperone Imported into the Nucleus with Help of the SMN Complex
John den Engelsman et al.
PLOS ONE (2013)
Regulated structural transitions unleash the chaperone activity of αB-crystallin
Jirka Peschek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Proteomics and Phosphoproteomics Analysis of Human Lens Fiber Cell Membranes
Zhen Wang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
αB-crystallin, a small heat shock protein, modulates NF-κB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-α induced cytotoxicity
Amit S. Adhikari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove
A. R. Clark et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death
Rongyu Li et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation
Ahmet Arac et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
N-terminal domain of αB-crystallin provides a conformational switch for multimerization and structural heterogeneity
Stefan Jehle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach
Nathalie Braun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Polydispersity of αB-Crystallin Is Rationalized by an Interconverting Polyhedral Architecture
Andrew J. Baldwin et al.
STRUCTURE (2011)
The small heat shock protein αA-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis
Mi Deng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Serine 59 Phosphorylation of αB-Crystallin Down-regulates Its Anti-apoptotic Function by Binding and Sequestering Bcl-2 in Breast Cancer Cells
Nathalie Launay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The p.G154S mutation of the alpha-B crystallin gene (CRYAB) causes late-onset distal myopathy
Peter Reilich et al.
NEUROMUSCULAR DISORDERS (2010)
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function
Arthur Laganowsky et al.
PROTEIN SCIENCE (2010)
Age-Dependent Deamidation of Lifelong Proteins in the Human Lens
Peter G. Hains et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
Suppression of GFAP toxicity by αB-crystallin in mouse models of Alexander disease
Tracy L. Hagemann et al.
HUMAN MOLECULAR GENETICS (2009)
Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20
C. Bagneris et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The eye lens chaperone α-crystallin forms defined globular assemblies
Jirka Peschek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Age-Related Changes in the Spatial Distribution of Human Lens α-Crystallin Products by MALDI Imaging Mass Spectrometry
Angus C. Grey et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA)
Leslie Richter et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)
Structural and functional roles of deamidation and/or truncation of N- or C-termini in human αA-Crystallin
Jose M. Chaves et al.
BIOCHEMISTRY (2008)
αB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis
Emily A. Whiston et al.
INFECTION AND IMMUNITY (2008)
Small heat shock protein activity is regulated by variable oligomeric substructure
Justin L. P. Benesch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Effect of phosphorylation on αB-crystallin:: Differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of αB-crystallin and its phosphorylation-mimicking mutant
Md. Falz Ahmad et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Differential regulation of small heat shock proteins in transgenic mouse models of neurodegenerative diseases
Jiou Wang et al.
NEUROBIOLOGY OF AGING (2008)
Hsp27 (HspB1) and αB-crystallin (HspB5) as therapeutic targets
Andr-Patrick Arrigo et al.
FEBS LETTERS (2007)
Protective and therapeutic role for αB-crystallin in autoimmune demyelination
Shalina S. Ousman et al.
NATURE (2007)
Assigning in vivo carbamylation and acetylation in human lens proteins using tandem mass spectrometry and database searching
Zee-Yong Park et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2007)
Mimicking phosphorylation of alpha B-crystallin affects its chaperone activity
Heath Ecroyd et al.
BIOCHEMICAL JOURNAL (2007)
Cell signaling pathways to αB-crystallin following stresses of the cytoskeleton
Nathalie Launay et al.
EXPERIMENTAL CELL RESEARCH (2006)
Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: Does deamidation contribute to crystallin insolubility?
P. A. Wilmarth et al.
JOURNAL OF PROTEOME RESEARCH (2006)
αB-Crystallin mutation in dilated cardiomyopathies:: Low prevalence in a consecutive series of 200 unrelated probands
Andrea Pilotto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family
Mugen Liu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
αB-crystallin mutation in dilated cardiomyopathy
N Inagaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
A novel αB-crystallin mutation associated with autosomal dominant congenital lamellar cataract
YZ Liu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
alpha B-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer
JV Moyano et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Nuclear import of αB-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G
J den Englesman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Alpha B-crystallin, a new independent marker for poor prognosis in head and neck cancer
D Chin et al.
LARYNGOSCOPE (2005)
α-Crystallin localizes to the leading edges of migrating lens epithelial cells
R Maddala et al.
EXPERIMENTAL CELL RESEARCH (2005)
The small heat shock protein αB-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3
MC Kamradt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm
BC Searle et al.
JOURNAL OF PROTEOME RESEARCH (2005)
Characterization of covalent multimers of crystallins in aging human lenses
OP Srivastava et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphorylation of αB-crystallin alters chaperone function through loss of dimeric substructure
JA Aquilina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ageing and vision: structure, stability and function of lens crystallins
H Bloemendal et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)
Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q
DS Mackay et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2003)
Mechanism of chaperone function in small heat-shock proteins -: Phosphorylation-induced activation of two-mode binding in αB-crystallin
HA Koteiche et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mimicking phosphorylation of αB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis
LE Morrison et al.
CIRCULATION RESEARCH (2003)
Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations
D Selcen et al.
ANNALS OF NEUROLOGY (2003)
The small heat shock protein αB-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation
MC Kamradt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Shotgun identification of protein modifications from protein complexes and lens tissue
MJ MacCoss et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and αB-crystallin to aggresomes
H Ito et al.
JOURNAL OF BIOCHEMISTRY (2002)
α-crystallin chaperone-like activity and membrane binding in age-related cataracts
BA Cobb et al.
BIOCHEMISTRY (2002)
Ser-59 is the major phosphorylation site in αB-crystallin accumulated in the brains of patients with Alexander's disease
K Kato et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Alpha-b crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans
V Berry et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
αB crystallin translocation and phosphorylation:: Signal transduction pathways and preconditioning in the isolated rat heart
P Eaton et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
In vivo carbamylation and acetylation of water-soluble human lens αB-crystallin lysine 92
VN Lapko et al.
PROTEIN SCIENCE (2001)
Phosphorylation-induced Change of the Oligomerization state of αB-crystallin
K Ito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Does post-translational modification influence chaperone-like activity of alpha-crystallin? I. Study on phosphorylation
A Kamei et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2001)
αB-crystallin gene induction and phosphorylation by MKK6-activated p38 -: A potential role for αB-crystallin as a target of the p38 branch of the cardiac stress response
HE Hoover et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage
SRA Hanson et al.
EXPERIMENTAL EYE RESEARCH (2000)
Subunit exchange of small heat shock proteins -: Analysis of oligomer formation of αA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations
MP Bova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Molecular chaperones and the aging process
C Soti et al.
BIOGERONTOLOGY (2000)