4.4 Article

Evaluation of the resection efficiency and safety of an enhanced power plasma generator using cadaveric intervertebral discs

Journal

BIOMEDICAL ENGINEERING LETTERS
Volume 13, Issue 1, Pages 57-64

Publisher

SPRINGERNATURE
DOI: 10.1007/s13534-022-00253-9

Keywords

Herniated intervertebral disc; Percutaneous plasma disc decompression; Back pain; Interventional spine procedure

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This study evaluates the efficiency and safety of a newly designed enhanced plasma generator for the treatment of spinal problems. The results show that the device can effectively remove a part of the intervertebral disc without causing damage to the surrounding tissues, providing potential benefits for future spine clinics.
Plasma energy has been used to provide minimally invasive interventional treatment for spinal problems. However, this procedure has been used for limited indications mainly because of its small resection range. To overcome this problem, we designed the enhanced power plasma device. This device seeks to maximize the resection area by modifying the electrode arrangement and enhancing the maximum electric power. The purpose of this study is to assess the efficiency and safety of this newly designed plasma generator, a device for percutaneous disc decompression. We performed an intradiscal procedure on 7 fresh human cadaver lumbar spine specimens using the enhanced power plasma under C-arm fluoroscopic guidance at various voltages. As a result, the volume of the removed area was proportional to the applied magnitude of the electric power level. In particular, under the high-power level condition after 500 s treatment, nearly the entire nucleus pulposus was eliminated. The generated plasma density also tends to grow along with the given electric power. The highest level of temperature rise did not exceed the level that would lead to degeneration in the collagen tissue of the intervertebral disc. Histopathologic examination also demonstrated that there was no thermal damage to the surrounding neural tissues. In conclusion, we speculate that the concepts of this newly designed enhanced plasma generator could be applied to remove huge disc materials without thermal or structural damage to the adjacent target tissues in future spine clinics.

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