4.5 Article

Using bioinformatics analysis to screen abnormal methylated differentially expressed hub genes of Kawasaki disease and construct diagnostic model

Related references

Note: Only part of the references are listed.
Review Pathology

Programmed death ligand-1 (PD-L1) as a predictive marker for immunotherapy in solid tumours: a guide to immunohistochemistry implementation and interpretation

Elizabeth C. Paver et al.

Summary: Immunotherapy with checkpoint inhibitors, particularly PD-1/PD-L1 inhibitors, has shown efficacy in treating non-small cell lung cancer and melanoma. As clinical trials continue to expand the approved indications for these inhibitors, pathologists need to be familiar with the different PD-L1 testing methods and their impact on therapeutic decisions.

PATHOLOGY (2021)

Article Genetics & Heredity

In silico Identification of 10 Hub Genes and an miRNA-mRNA Regulatory Network in Acute Kawasaki Disease

Jin Ma et al.

Summary: In this study, hub genes in acute KD patients were identified using bioinformatics analysis, along with the construction of an miRNA-mRNA regulatory network associated with acute KD. The study also predicted target genes for differentially expressed miRNAs (DE-miRNAs) and found potential pathways enriched with hub genes. These findings provide new insights into the pathogenesis of acute KD and may contribute to its diagnosis and treatment.

FRONTIERS IN GENETICS (2021)

Article Multidisciplinary Sciences

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data

Matthew C. Altman et al.

Summary: This article describes the development of a new fixed repertoire of transcriptional modules, BloodGen3, for the analysis and interpretation of blood transcriptome data. The construction of this repertoire is based on a large-scale analysis of 985 blood transcriptome profiles across sixteen immunological and physiological states. The authors show that this well-characterized and well-supported transcriptional module repertoire can be employed for the analysis and interpretation of blood transcriptome profiles within and across patient cohorts.

NATURE COMMUNICATIONS (2021)

Review Immunology

CD2 Immunobiology

Christian Binder et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Pediatrics

Revision of diagnostic guidelines for Kawasaki disease (6th revised edition)

Tohru Kobayashi et al.

PEDIATRICS INTERNATIONAL (2020)

Article Pediatrics

Increase expression of CD177 in Kawasaki disease

Ying-Hsien Huang et al.

PEDIATRIC RHEUMATOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999-2010 in Japan

Ryuji Fukazawa et al.

CIRCULATION JOURNAL (2018)

Article Pediatrics

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature

Victoria J. Wright et al.

JAMA PEDIATRICS (2018)

Article Biochemical Research Methods

ChAMP: updated methylation analysis pipeline for Illumina BeadChips

Yuan Tian et al.

BIOINFORMATICS (2017)

Review Immunology

Immunogenetics of juvenile idiopathic arthritis: A comprehensive review

Aimee O. Hersh et al.

JOURNAL OF AUTOIMMUNITY (2015)

Article Biochemistry & Molecular Biology

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biochemistry & Molecular Biology

Polymorphisms in the IL2RA and IL2RB Genes in Inflammatory Bowel Disease Risk

Dorra Bouzid et al.

GENETIC TESTING AND MOLECULAR BIOMARKERS (2013)

Review Public, Environmental & Occupational Health

Epidemiology of Kawasaki Disease in Asia, Europe, and the United States

Ritei Uehara et al.

JOURNAL OF EPIDEMIOLOGY (2012)

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

Article Biochemical Research Methods

pROC: an open-source package for R and S plus to analyze and compare ROC curves

Xavier Robin et al.

BMC BIOINFORMATICS (2011)

Article Immunology

Pathogenesis of Kawasaki disease

K. Takahashi et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Cytokine Genetic Polymorphisms and Susceptibility to Kawasaki Disease in Taiwanese Children

Ken-Pen Weng et al.

CIRCULATION JOURNAL (2010)

Article Immunology

The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease

S. Jia et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)

Article Biochemistry & Molecular Biology

Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk

Maria L. Cavanillas et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2010)

Article Pediatrics

Molecular Genetics of Kawasaki Disease

Yoshihiro Onouchi

PEDIATRIC RESEARCH (2009)

Article Biochemical Research Methods

lumi:: a pipeline for processing Illumina microarray

Pan Du et al.

BIOINFORMATICS (2008)

Review Biochemistry & Molecular Biology

Genomic DNA methylation: the mark and its mediators

RJ Klose et al.

TRENDS IN BIOCHEMICAL SCIENCES (2006)

Article Medical Laboratory Technology

Association of IL-1Ra gene polymorphism, but no association of IL-1 beta and IL-4 gene polymorphisms, with Kawasaki disease

SF Wu et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2005)

Article Pediatrics

CD25+ CD4+ regulatory T cells in patients with Kawasaki disease

K Furuno et al.

JOURNAL OF PEDIATRICS (2004)

Article Computer Science, Artificial Intelligence

Random forests

L Breiman

MACHINE LEARNING (2001)