4.5 Article

Adult pilomyxoid astrocytoma presenting in the temporal lobe

Journal

HELIYON
Volume 9, Issue 1, Pages -

Publisher

CELL PRESS
DOI: 10.1016/j.heliyon.2023.e12909

Keywords

Pilomyxoid astrocytoma; PMA; Pilocytic astrocytoma; PA; Adult; Temporal lobe

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Pilomyxoid astrocytoma (PMA) is a rare variant of astrocytoma that is usually found in the hypothalamic and chiasmatic areas in children. PMA shares many histopathological features with Pilocytic astrocytoma (PA), but has notable differences in radiological and histopathological findings, and is known to exhibit more aggressive clinical progression. We report a rare case of PMA in a 25-year-old female involving the temporal lobe, presenting with recurrent partial seizures. This case is unique due to the uncommon location, unusual age group, and distinctive radiological features.
Pilomyxoid astrocytoma (PMA) is a rare variant of astrocytoma that is usually present in the hypothalamic and chiasmatic areas in the paediatric population. PMA shares many similar his-topathological features to Pilocytic astrocytoma (PA), with some notable differences in its radiological and histopathological findings. On the contrary, PMA has been reported to behave more aggressively in its clinical progression than PA. Here, we describe a rare case of PMA in a 25-year-old female involving the temporal lobe, presenting with recurrent partial seizures. To our knowledge, this is the first reported case of PMA presenting in the temporal lobe in an adult female with an atypical location of the tumour, uncommon age group, and unusual radiological features being unique in this case report.

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