Journal
CELL STEM CELL
Volume 16, Issue 5, Pages 453-454Publisher
CELL PRESS
DOI: 10.1016/j.stem.2015.04.018
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Funding
- NIGMS NIH HHS [T32 GM007215, R01 GM049975] Funding Source: Medline
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3D organ buds that can recapitulate organ function have myriad applications for regenerative and personalized medicine. Here, Takebe et al. (2015) describe a generalized method for organ bud formation, demonstrating that mechanosensitive mesenchymal stem cells drive condensation of heterotypic cell mixtures to create buds from diverse organs.
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