4.8 Article

The translational paradigm of nanobiomaterials: Biological chemistry to modern applications

Journal

MATERIALS TODAY BIO
Volume 17, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.mtbio.2022.100463

Keywords

Nanobiomaterial; Translational applications; Cancer therapy; Drug delivery

Funding

  1. KIIT UNIVERSITY [BT/INF/22/SP42155/2021]
  2. Slovenian Research Agency (ARRS) [P1-0143, PR-11681]
  3. NRF Korea [2021R1A6A1A03038785, 2021R1F1A1055694]
  4. Kwangwoon University
  5. National Research Foundation of Korea [2021R1A6A1A03038785] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Nanotechnology has emerged as a revolutionary technology with a wide range of applications in various industries. Nanobiomaterials, derived from biological elements, have shown great potential in the biomedical field due to their biocompatibility and unique properties. The commercialization of nanotechnology has led to the development of nano-scaffolds, implants, and biosensors, revolutionizing the biomedical field. This review explores the diverse emerging applications of nanobiomaterials and their mechanistic advancements.
Recently nanotechnology has evolved as one of the most revolutionary technologies in the world. It has now become a multi-trillion-dollar business that covers the production of physical, chemical, and biological systems at scales ranging from atomic and molecular levels to a wide range of industrial applications, such as electronics, medicine, and cosmetics. Nanobiomaterials synthesis are promising approaches produced from various biological elements be it plants, bacteria, peptides, nucleic acids, etc. Owing to the better biocompatibility and biological approach of synthesis, they have gained immense attention in the biomedical field. Moreover, due to their scaled -down sized property, nanobiomaterials exhibit remarkable features which make them the potential candidate for different domains of tissue engineering, materials science, pharmacology, biosensors, etc. Miscellaneous char-acterization techniques have been utilized for the characterization of nanobiomaterials. Currently, the commer-cial transition of nanotechnology from the research level to the industrial level in the form of nano-scaffolds, implants, and biosensors is stimulating the whole biomedical field starting from bio-mimetic nacres to 3D printing, multiple nanofibers like silk fibers functionalizing as drug delivery systems and in cancer therapy. The contribution of single quantum dot nanoparticles in biological tagging typically in the discipline of genomics and proteomics is noteworthy. This review focuses on the diverse emerging applications of Nanobiomaterials and their mechanistic advancements owing to their physiochemical properties leading to the growth of industries on different biomedical measures. Alongside the implementation of such nanobiomaterials in several drug and gene delivery approaches, optical coding, photodynamic cancer therapy, and vapor sensing have been elaborately discussed in this review. Different parameters based on current challenges and future perspectives are also dis-cussed here.

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