4.7 Article

Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid

Journal

ACS APPLIED NANO MATERIALS
Volume 6, Issue 1, Pages 1-9

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsanm.2c02645

Keywords

CuWO4; inorganic nanomaterials; electrochemical approach; real -world samples; uric acid

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Researchers aim to develop multifunctional materials with superior efficiency for large-scale electrochemical sensor applications that are nontoxic, low-cost, and simple to produce. Uric acid (UA) was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a CuWO4 electrode. The CuWO4 electrode exhibited a superior electrochemical oxidation peak current compared to the bare electrode. The CuWO4-modified sensor had wide linear ranges and a low limit of detection.
Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a superactive Wolframite structure of CuWO4. CuWO4 was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO4 provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO4 exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i-t techniques. Furthermore, the CuWO(4)modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO4-modified sensor has great stability and reproducibility.

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