Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report

IntroductionLiver transplantation is a risk factor for premalignant and malignant changes of the duodenum. De novo duodenal malignancy is seldom reported after liver transplantation. Case ReportThe present study reports a case of an asymptomatic 67-year-old male patient who underwent liver transplantation more than 10 years ago and subsequently developed duodenal malignancy. Endoscopic biopsy of the de novo duodenal malignancy indicated duodenal carcinoma and pancreatoduodenectomy (PD) was performed. The patient was successfully discharged 12 days after the surgery. A metastatic lesion occurred at the right seventh rib 14 months after the pancreatoduodenectomy. Postoperative pathological examination indicated hepatocellular carcinoma metastasis. ConclusionsTo the best of our knowledge, this case type has not been previously reported. The present study sheds light on the development, the treatment, the prognosis, and the management of a new type of de novo duodenal malignancy.

Automated summary

This study reports a case of de novo duodenal malignancy in a patient who had undergone liver transplantation. The patient was diagnosed with duodenal carcinoma and subsequently underwent pancreatoduodenectomy. A metastatic lesion occurred 14 months after the surgery, which was found to be hepatocellular carcinoma metastasis.