4.5 Article

Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report

Journal

CHILDREN-BASEL
Volume 9, Issue 11, Pages -

Publisher

MDPI
DOI: 10.3390/children9111767

Keywords

platelet gel; nasal septum; septal tissue; prematurity; non-invasive ventilation

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This study evaluated the use of CBPG in regenerating the nasal septum of a premature patient undergoing non-invasive ventilation, showing promising results with partial regeneration observed. The use of platelet gel may be a potential alternative to surgical treatment for patients with severe nasal septum damage.
Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation. Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes. Results: A partial but satisfactory regeneration of the patient's nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage). Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum.

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