Who Seeks Clear Aligner Therapy? A European Cross-National Real-World Data Analysis

A key step prior to clear aligner therapy (CAT) is the clinical examination and case selection, which includes understanding the specific orthodontic problem to be managed and the wider evaluation of oral health. Seeking CAT may further differ along sociodemographic parameters or across countries, as may perceived orthodontic treatment needs and oral health. We aimed to characterize patients seeking CAT across five European countries. Anonymized real-life data from one large CAT provider (DrSmile, Berlin, Germany) was retrospectively sampled for the period 1 November 2021-31 December 2021. A total of 15,015 patients (68.4% females, 31.6% males, with an age range of 18-81 years, median 30.0 years) were included. The cross-national comparison revealed a significant difference in gender distribution (p < 0.001/Chi-square), with the highest proportion of males in Italy (434/1199, 36.2%) and the lowest in Poland (457/1600, 28.6%); generally, more females sought CAT. The largest motivational factor in all countries for seeking CAT was crowding, in both males and females. By and large, patients paid out of pocket for CAT. The prevalence of caries, periodontitis, and craniomandibular dysfunction as well as the numbers of missing teeth were generally low, albeit with significant differences between sociodemographic groups and countries for caries and periodontitis. Patients seeking CAT showed a low prevalence in oral conditions but differed in their sociodemographic characteristics across countries. Dentists and orthodontists should consider these country-specific differences when planning CAT.

Automated summary

The key step prior to clear aligner therapy (CAT) is to examine and select suitable cases, which includes understanding the orthodontic problem and evaluating oral health. The characteristics of patients seeking CAT may differ among European countries. This study retrospectively analyzed anonymized data from a large CAT provider in five European countries. The results showed differences in gender distribution and motivations across countries, as well as low prevalence of oral conditions among patients seeking CAT.