Recent Advances in Surface Plasmon Resonance Microscopy

Surface plasmon resonance microscopy (SPRM) is a versatile technique for biosensing and imaging that facilitates high-sensitivity, label-free, real-time characterization. To date, SPR technology has been successfully commercialized and its performance has continued to improve. However, this method is inhibited by low spatial resolution and the inability to achieve single-molecule detection. In this report, we present an overview of SPRM research progress in the field of plasma imaging and sensing. A brief review of the technological advances in SPRM is outlined, as well as research progress in important applications. The combination of various new techniques with SPRM is emphasized. Finally, the current challenges and outlook of this technique are discussed.

Automated summary

Surface plasmon resonance microscopy (SPRM) is a versatile technique for biosensing and imaging that enables high-sensitivity, label-free, real-time characterization. This report provides an overview of the research progress in SPRM for plasma imaging and sensing, summarizing the technological advances and important applications. The combination of various new techniques with SPRM is emphasized.