4.7 Review

Recent Development in Plasmonic Nanobiosensors for Viral DNA/RNA Biomarkers

Journal

BIOSENSORS-BASEL
Volume 12, Issue 12, Pages -

Publisher

MDPI
DOI: 10.3390/bios12121121

Keywords

plasmonic nanomaterials; viral DNA; viral RNA; early diagnosis; nanobiosensors

Funding

  1. National Research Foundation of Korea (NRF) grant - Korea government (MSIT) [NRF-2022R1C1C1008797]
  2. National R&D Program through the NRF - Ministry of Science and ICT [NRF-2022M3H4A1A01005271]
  3. National Research Foundation of Korea [2022M3H4A1A01005271] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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This review introduces a new method of using plasmonic nanobiosensors to measure viral DNA/RNA and discusses their potential applications in early diagnosis and pathological interpretation.
Recently, due to the coronavirus pandemic, the need for early diagnosis of infectious diseases, including viruses, is emerging. Though early diagnosis is essential to prevent infection and progression to severe illness, there are few technologies that accurately measure low concentrations of biomarkers. Plasmonic nanomaterials are attracting materials that can effectively amplify various signals, including fluorescence, Raman, and other optical and electromagnetic output. In this review, we introduce recently developed plasmonic nanobiosensors for measuring viral DNA/RNA as potential biomarkers of viral diseases. In addition, we discuss the future perspective of plasmonic nanobiosensors for DNA/RNA detection. This review is expected to help the early diagnosis and pathological interpretation of viruses and other diseases.

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