Serum triglycerides level is independently associated with renal outcomes in patients with non-dialysis chronic kidney disease: Results from KNOW-CKD study

Article Cardiac & Cardiovascular Systems

Association of Left Ventricular Diastolic Dysfunction With Cardiovascular Outcomes in Patients With Pre-dialysis Chronic Kidney Disease: Findings From KNOW-CKD Study

Sang Heon Suh et al.

Summary: Left ventricular diastolic dysfunction is independently associated with adverse cardiovascular outcomes and all-cause mortality in patients with pre-dialysis chronic kidney disease.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Association Between Left Ventricular Geometry and Renal Outcomes in Patients With Chronic Kidney Disease: Findings From Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease Study

Sang Heon Suh et al.

Summary: Left ventricular (LV) geometry is significantly associated with adverse renal outcomes and all-cause mortality in patients with pre-dialysis chronic kidney disease (CKD). Specifically, eccentric hypertrophy (eLVH) and concentric hypertrophy (cLVH) are associated with increased risk of composite renal events, while concentric remodeling and cLVH are associated with increased risk of all-cause mortality.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Article Urology & Nephrology

Association of Serum Triglycerides and Renal Outcomes among 1.6 Million US Veterans

Melissa Soohoo et al.

Summary: The study suggests that elevated triglycerides (TGs) levels are associated with a higher incidence of chronic kidney disease (CKD) and a faster decline in renal function, independent of other components of metabolic syndrome (MetS). However, in CKD stages 4-5, the association between TGs and time to end-stage renal disease (ESRD) is null or inverse.

NEPHRON (2022)

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Review Nutrition & Dietetics

Dietary Lipids and Dyslipidemia in Chronic Kidney Disease

Zdzislaw Kochan et al.

Summary: Chronic kidney disease (CKD) is associated with altered lipid metabolism, leading to increased risk of cardiovascular disease. Unsaturated fatty acids have shown cardioprotective effects by improving blood lipid profile and reducing cardiovascular risk, making dietary lipids crucial in nutritional management of CKD patients.

NUTRIENTS (2021)

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Article Cardiac & Cardiovascular Systems

Inflammation Alters Relationship Between High-Density Lipoprotein Cholesterol and Cardiovascular Risk in Patients With Chronic Kidney Disease: Results From KNOW-CKD

Jae Young Kim et al.

Summary: The relationship between HDL-C level and adverse cardiovascular outcomes in Korean patients with chronic kidney disease can be modified by inflammation, leading to reverse trends in the association.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

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Article Physiology

High-Fat Diet Increased Oxidative Stress and Mitochondrial Dysfunction Induced by Renal Ischemia-Reperfusion Injury in Rat

Priyanka N. Prem et al.

Summary: High-fat diet consumption can induce renal lipotoxicity and metabolic dyshomeostasis, compromising kidney function and exacerbating renal ischemia-reperfusion injury.

FRONTIERS IN PHYSIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems