Effect of remote ischaemic conditioning on left ventricular function in ST-segment elevation myocardial infarction patients: The CONDI-2 echocardiographic sub-study

Article Cardiac & Cardiovascular Systems

Effects of late, repetitive remote ischaemic conditioning on myocardial strain in patients with acute myocardial infarction

J. Ranjit Arnold et al.

Summary: Remote ischaemic conditioning (CRIC) following primary percutaneous coronary intervention (P-PCI) can improve longitudinal strain in infarct-related segments and attenuate the increase in circumferential strain in remote segments.

BASIC RESEARCH IN CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Cardioprotection of Repeated Remote Ischemic Conditioning in Patients With ST-Segment Elevation Myocardial Infarction

Shaomin Chen et al.

Summary: This study investigated the effect of repeated remote ischemic conditioning (RIC) started early after primary percutaneous coronary intervention (PCI) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). The results showed that repeated RIC can improve LV function and reduce plasma NT proBNP levels in patients with STEMI.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity

Carlos Galan-Arriola et al.

Summary: This study demonstrates that RIPC applied immediately before each doxorubicin injection can preserve cardiac contractility, result in significantly higher long-term left ventricular ejection fraction, and less cardiac fibrosis in a translatable large-animal model of AIC. RIPC is able to prevent mitochondrial fragmentation and dysregulated autophagy from AIC early stages, suggesting it as a promising intervention for testing in clinical trials for AIC.

CARDIOVASCULAR RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy

Rohin Francis et al.

Summary: The study found that limb remote ischaemic conditioning did not have a significant effect on myocardial infarct size and left ventricular ejection fraction. Cardiovascular magnetic resonance scans conducted both acutely and at 6 months showed no reduction in infarct size or improvement in heart function with limb RIC.

BASIC RESEARCH IN CARDIOLOGY (2021)

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