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Related references

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Article Gastroenterology & Hepatology

The Sequential Application of Baveno VII Criteria and VITRO Score Improves Diagnosis of Clinically Significant Portal Hypertension

Mathias Jachs et al.

Summary: Baveno VII proposed criteria for clinically significant portal hypertension in compensated advanced chronic liver disease (cACLD) but many patients remain unclassified. The sequential application of VITRO decreased the number of unclassified patients and improved prognostication.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2023)

Article Gastroenterology & Hepatology

Baveno-VII criteria to predict decompensation and initiate non-selective beta-blocker in compensated advanced chronic liver disease patients

Yu Jun Wong et al.

Summary: The study aimed to validate the utility of Baveno-VII criteria in predicting decompensation in cACLD patients. The results showed that non-invasive assessment of CSPH can predict the risk of liver decompensation in these patients.

CLINICAL AND MOLECULAR HEPATOLOGY (2023)

Article Gastroenterology & Hepatology

Distinct structural and dynamic components of portal hypertension in different animal models and human liver disease etiologies

Philipp Koenigshofer et al.

Summary: The study found that the relative contribution of static fibrosis to the severity of portal hypertension (PH) varies by type of liver injury. In addition to hyperdynamic circulation, increased bile acids, VWF-Ag, IL-6, and HA appear to indicate a pronounced dynamic component of PH in patients.

HEPATOLOGY (2022)

Article Gastroenterology & Hepatology

A Combined Baveno VII and Spleen Stiffness Algorithm to Improve the Noninvasive Diagnosis of Clinically Significant Portal Hypertension in Patients With Compensated Advanced Chronic Liver Disease

Elton Dajti et al.

Summary: The addition of spleen stiffness measurement (SSM) improves the diagnostic algorithm for clinically significant portal hypertension (CSPH) in patients with compensated advanced chronic liver disease.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2022)

Article Gastroenterology & Hepatology

Non-invasive tests for clinically significant portal hypertension after HCV cure

Georg Semmler et al.

Summary: This study analyzed the diagnostic and prognostic value of non-invasive tests for portal hypertension in patients who have been cured of HCV infection. The results showed that liver stiffness measurement had an increased correlation with hepatic venous pressure gradient after treatment.

JOURNAL OF HEPATOLOGY (2022)

Review Gastroenterology & Hepatology

The Value of Liver and Spleen Stiffness for Evaluation of Portal Hypertension in Compensated Cirrhosis

Thomas Reiberger

Summary: Noninvasive measures for detecting clinically significant portal hypertension (CSPH) are important for patients with compensated advanced chronic liver disease. Alterations in the biomechanical properties of the liver and spleen, measured by tissue elastography, offer valuable alternatives to invasive procedures like liver biopsy and hepatic venous pressure gradient (HVPG) measurements. Liver stiffness (LS) and spleen stiffness (SS) measurements correlate well with CSPH severity, making them useful in monitoring treatment response and assessing portal hypertension (PH) improvement.

HEPATOLOGY COMMUNICATIONS (2022)

Article Gastroenterology & Hepatology

Noninvasive Risk Stratification After HCV Eradication in Patients With Advanced Chronic Liver Disease

Georg Semmler et al.

Summary: This study confirms the predictive value of noninvasive markers (LSM and VITRO) in determining the development of hepatic decompensation and hepatocellular carcinoma in patients with chronic liver disease caused by hepatitis C after cure. By combining these markers, it is possible to more accurately identify the risk of hepatic decompensation in patients in the future.

HEPATOLOGY (2021)

Review Gastroenterology & Hepatology

β-blockers in advanced cirrhosis: More friend than enemy

Ki Tae Yoon et al.

Summary: NSBB therapy in cirrhotic patients is effective in preventing bleeding, but may have detrimental effects in decompensated cirrhosis. While some studies suggest harmful effects of NSBBs, overall, using beta-blockers in cirrhosis seems to outweigh the risks and provide more benefits.

CLINICAL AND MOLECULAR HEPATOLOGY (2021)

Editorial Material Gastroenterology & Hepatology

The cutoff of transient elastography for the evaluation of portal hypertension should be different according to the etiology?

Beom Kyung Kim

CLINICAL AND MOLECULAR HEPATOLOGY (2021)

Article Gastroenterology & Hepatology

The cut-off value of transient elastography to the value of hepatic venous pressure gradient in alcoholic cirrhosis

Se Ri Ryu et al.

Summary: The study investigated the correlation between liver stiffness value, LS to platelet ratio, LS-spleen diameter-to-platelet ratio score and HVPG in alcoholic cirrhosis patients compared to viral cirrhosis. The results showed that liver stiffness value was higher in alcoholic cirrhosis patients than viral cirrhosis patients.

CLINICAL AND MOLECULAR HEPATOLOGY (2021)

Article Gastroenterology & Hepatology

Prevention of First Decompensation in Advanced Chronic Liver Disease

Mattias Mandorfer et al.

CLINICS IN LIVER DISEASE (2021)

Article Multidisciplinary Sciences

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy

Thomas Reiberger et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2020)

Review Gastroenterology & Hepatology

Noninvasive Diagnostics for Portal Hypertension: A Comprehensive Review

Mattias Mandorfer et al.

SEMINARS IN LIVER DISEASE (2020)

Review Gastroenterology & Hepatology

Managing liver cirrhotic complications: Overview of esophageal and gastric varices

Cosmas Rinaldi Adithya Lesmana et al.

CLINICAL AND MOLECULAR HEPATOLOGY (2020)

Article Gastroenterology & Hepatology

The von Willebrand Factor antigen to platelet ratio (VITRO) score predicts hepatic decompensation and mortality in cirrhosis

Remy Schwarzer et al.

JOURNAL OF GASTROENTEROLOGY (2020)