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Bicyclobutanes as unusual building blocks for complexity generation in organic synthesis

COMMUNICATIONS CHEMISTRY (2023)

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Summary: This review discusses the recent developments in the synthesis and functionalization of bicyclo[1.1.0]butane (BCB), as well as the applications of these strained rings in synthesis and drug discovery. BCBs have unique chemistry that has captivated organic chemists for a long time, and recent research has shown that BCBs can be powerful synthetic tools.

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